Cambrosio Alberto, Keating Peter, Mercier Simon, Lewison Grant, Mogoutov Andrei
Department of Social Studies of Medicine, McGill University, Montreal, QC, Canada.
Eur J Cancer. 2006 Dec;42(18):3140-8. doi: 10.1016/j.ejca.2006.07.020. Epub 2006 Oct 31.
Cancer research is one of the principal targets of translational research, yet the nature of the relationships between different forms of cancer research remains controversial. The paper examines publications in the cancer field during the 1980-2000 period. A network analysis software program was used to map evolving patterns of inter-citations between cancer publications, their different research levels and the transformation of their relational content. Both inter-citation and content maps provide striking evidence of the consolidation in the 1990s of a translational interface that was practically non existent a few decades before. In 1980, research was polarized according to the allegiance to either a clinical or a laboratory style. This same duality obtains in the year 2000, albeit with the additional presence of a third, biomedical player whose activities are similarly structured by a common orientation, rather than by an exclusive commitment to a specific sub-domain.
癌症研究是转化研究的主要目标之一，但不同形式的癌症研究之间关系的本质仍存在争议。本文考察了1980年至2000年期间癌症领域的出版物。使用网络分析软件程序来绘制癌症出版物之间相互引用的演变模式、它们不同的研究水平以及其关系内容的转变。相互引用图和内容图都提供了显著证据，证明了在20世纪90年代形成了一个几十年前实际上不存在的转化界面。1980年，研究根据对临床或实验室风格的忠诚而两极分化。2000年同样存在这种二元性，尽管还额外出现了第三个参与者，即生物医学领域，其活动同样由一个共同的方向构建，而不是仅仅专注于一个特定的子领域。
