Mertes H, Pennings G
Centre for Environmental Philosophy and Bioethics, Ghent University, Ghent, Belgium.
Hum Reprod. 2007 Mar;22(3):629-34. doi: 10.1093/humrep/del431. Epub 2006 Nov 1.
The future success of stem cell research by means of somatic cell nuclear transfer (SCNT) depends on a sufficient supply of human oocytes. However, oocyte donation presents certain risks for the donor, and concerns for women's welfare are rightly vocalized. At the same time, these risks are comparable with the risks faced by other healthy research subjects. Thus, research donation can withstand ethical scrutiny if it fulfils the same conditions as other research involving healthy human subjects. Specifically, this means that the benefits of the research project need to outweigh the harms, that risks must be minimized, that informed consent has to be guaranteed by averting undue inducement and the recruitment of vulnerable women and that donors can and should be reimbursed for their research participation.
通过体细胞核移植（SCNT）进行的干细胞研究未来能否成功取决于人类卵母细胞的充足供应。然而，卵母细胞捐赠给捐赠者带来了一定风险，对女性福利的担忧也得到了合理表达。与此同时，这些风险与其他健康研究对象所面临的风险相当。因此，如果研究捐赠满足与其他涉及健康人类受试者的研究相同的条件，那么它就能经受住伦理审查。具体而言，这意味着研究项目的益处必须大于危害，风险必须降至最低，必须通过避免不当诱导和招募弱势女性来确保知情同意，并且捐赠者能够且应该因其参与研究而获得补偿。
