Schnadower David, Agarwal Chhavi, Oberfield Sharon E, Fennoy Ilene, Pusic Martin
Division of Pediatric Emergency Medicine, Morgan Stanley Children's Hospital of New York-Presbyterian, Columbia University Medical Center, New York, NY 10032, USA.
Pediatrics. 2006 Nov;118(5):2226-30. doi: 10.1542/peds.2006-1170.
Nutritional rickets and osteomalacia are reemerging in Western societies, particularly in young children and in adolescents of African or Asian descent. Hypocalcemic seizures resulting from vitamin D deficiency are rare in adolescents, whereas fractures caused by seizures without evidence of direct trauma have not yet been reported in this population. We present an unusual case of secondary bilateral femoral fractures caused by hypocalcemic seizures in a 17-year-old boy with primary vitamin D deficiency. We examine the epidemiology and the clinical presentation of rickets and osteomalacia in the adolescent population, the risk of secondary injuries in patients with seizures, and the evaluation and management of hypocalcemic seizures and primary vitamin D deficiency.
营养性佝偻病和骨软化症在西方社会正再度出现,尤其是在幼儿以及非洲或亚洲裔青少年中。维生素D缺乏导致的低钙血症性惊厥在青少年中较为罕见,而在该人群中,尚无无直接创伤证据的惊厥所致骨折的相关报道。我们报告了一例罕见病例,一名17岁原发性维生素D缺乏的男孩因低钙血症性惊厥导致双侧股骨骨折。我们研究了青少年人群中佝偻病和骨软化症的流行病学及临床表现、惊厥患者继发性损伤的风险,以及低钙血症性惊厥和原发性维生素D缺乏的评估与管理。