Oki J, Takedatsu M, Itoh J, Yano K, Cho K, Okuno A
Department of Pediatrics, Asahikawa Medical College, Japan.
Brain Dev. 1991;13(2):132-4. doi: 10.1016/s0387-7604(12)80122-7.
We present a case of a one-month-old infant with hypocalcemia and rickets, with symptoms of focal seizures. The ictal EEG showed left occipital spikes spreading over all of the left hemisphere. From the laboratory studies, we concluded that a low maternal circulating level of vitamin D would cause infantile hypocalcemia and rickets, while immature renal response to parathyroid hormone and transient hypoparathyroidism in infancy would induce hyperphosphatemia. Hypocalcemia may be an important factor in the cause of focal seizures which start even after the age of one month. Further, investigation of maternal vitamin D levels should be done in infantile hypocalcemia.
我们报告一例1个月大患有低钙血症和佝偻病且伴有局灶性癫痫发作症状的婴儿。发作期脑电图显示左枕叶棘波扩散至整个左半球。通过实验室研究，我们得出结论，母亲循环中维生素D水平低会导致婴儿低钙血症和佝偻病，而婴儿期肾脏对甲状旁腺激素反应不成熟以及短暂性甲状旁腺功能减退会导致高磷血症。低钙血症可能是即使在1个月龄后才开始的局灶性癫痫发作病因中的一个重要因素。此外，对于婴儿低钙血症应进行母亲维生素D水平的检测。
