Chroni Elisabeth, Argyriou Andreas A, Polychronopoulos Panagiotis, Sirrou Vassiliki
Dept of Neurology, Laboratory of Clinical Neurophysiology, University of Patras Medical School, 26504, Rion-Patras, Greece.
Clin Auton Res. 2006 Dec;16(6):396-400. doi: 10.1007/s10286-006-0376-x. Epub 2006 Nov 1.
The aim of this study was to collect normative data for sympathetic skin responses (SSR) elicited by electrical stimulus of the ipsilateral and contralateral peripheral nerves, and by magnetic stimulus of cervical cord. SSRs were measured at the mid-palm of both hands following electrical stimulation of the left median nerve at the wrist and magnetic stimulation at the neck in 40 healthy adult volunteers (mean age 52.2 +/- 12.2 years, 19 males). The onset latency, peak latency, amplitude and area were estimated in "P" type responses (i.e., waveforms with a larger positive, compared to negative, component). SSR onset and peak latency were prolonged when the electrical stimulus was applied at the contralateral side (i.e., the SSR recorded in the right palm P < 0.001). The onset latency was similar on both sides during cervical magnetic stimulation. However, peak latency was faster on the left side (P < 0.03). Comparison of electrical and magnetic stimulation revealed that both the onset and peak latency were shorter with magnetic stimulation (P < 0.001). The latency of a SSR varies depending on what type of stimulation is used and where the stimulus is applied. Electrically generated SSRs have a longer delay and the delay is prolonged at the contralateral side. These factors should be taken into account when interpreting SSR data.
本研究的目的是收集由同侧和对侧周围神经电刺激以及颈髓磁刺激诱发的交感神经皮肤反应（SSR）的正常数据。在40名健康成年志愿者（平均年龄52.2±12.2岁，19名男性）中，在手腕处电刺激左侧正中神经以及在颈部进行磁刺激后，测量双手掌中部的SSR。在“P”型反应（即与负向成分相比正向成分更大的波形）中估计起始潜伏期、峰值潜伏期、波幅和面积。当在对侧施加电刺激时（即右手掌记录的SSR，P<0.001），SSR的起始潜伏期和峰值潜伏期延长。在颈部磁刺激期间，两侧的起始潜伏期相似。然而，左侧的峰值潜伏期更快（P<0.03）。电刺激和磁刺激的比较显示，磁刺激的起始潜伏期和峰值潜伏期均较短（P<0.001）。SSR的潜伏期取决于所使用的刺激类型和刺激部位。电诱发的SSR延迟更长，且对侧的延迟会延长。在解释SSR数据时应考虑这些因素。
