健康个体和系统性红斑狼疮患者在免疫印迹上可检测到独特的、因人而异的抗体谱。
Healthy individuals and patients with systemic lupus erythematosus have unique, person-specific spectra of antibodies detectable on immunoblots.
作者信息
Shapiro P E, McAllister G, Lerner E A, Lerner M R
机构信息
Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut 06510.
出版信息
Clin Immunol Immunopathol. 1991 Apr;59(1):129-38. doi: 10.1016/0090-1229(91)90087-q.
PMID:1708313
Abstract
Through the technique of immunoblotting, the spectrum and organ specificity of antibodies in healthy individuals and patients with systemic lupus erythematosus were examined. It was demonstrated that healthy individuals and patients with autoimmune disease have antibodies, some tissue specific and some not tissue specific, which are present in a pattern that is unique to each individual.
摘要
通过免疫印迹技术，对健康个体和系统性红斑狼疮患者体内抗体的谱型和器官特异性进行了检测。结果表明，健康个体和自身免疫性疾病患者体内均存在抗体，其中一些具有组织特异性，一些则不具有组织特异性，且这些抗体以个体独特的模式存在。
Zotero 插件