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IgA and FcαRI: Pathological Roles and Therapeutic Opportunities.IgA 和 FcαRI:病理性作用和治疗机会。
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Specific antibody activity, glycan heterogeneity and polyreactivity contribute to the protective activity of S-IgA at mucosal surfaces.特异性抗体活性、聚糖异质性和多反应性有助于分泌型免疫球蛋白A在黏膜表面发挥保护作用。
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3
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4
Healthy individuals possess circulating antibodies against their indigenous faecal microflora as well as against allogenous faecal microflora: an immunomorphometrical study.健康个体拥有针对其自身粪便微生物群以及异体粪便微生物群的循环抗体:一项免疫形态计量学研究。
Epidemiol Infect. 1993 Oct;111(2):273-85. doi: 10.1017/s0950268800056983.
5
Characterization of human faecal flora by means of an improved fluoro-morphometrical method.通过一种改进的荧光形态计量学方法对人类粪便菌群进行表征。
Epidemiol Infect. 1993 Oct;111(2):265-72. doi: 10.1017/s0950268800056971.
6
Host-microflora interaction in systemic lupus erythematosus (SLE): colonization resistance of the indigenous bacteria of the intestinal tract.系统性红斑狼疮(SLE)中的宿主-微生物群相互作用:肠道固有细菌的定植抗性
Epidemiol Infect. 1994 Apr;112(2):367-73. doi: 10.1017/s0950268800057770.
7
Host-microflora interaction in systemic lupus erythematosus (SLE): circulating antibodies to the indigenous bacteria of the intestinal tract.系统性红斑狼疮(SLE)中的宿主-微生物群相互作用:针对肠道本土细菌的循环抗体。
Epidemiol Infect. 1995 Feb;114(1):133-41. doi: 10.1017/s0950268800051980.

本文引用的文献

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The resident faecal flora is determined by genetic characteristics of the host. Implications for Crohn's disease?肠道常驻菌群由宿主的遗传特征决定。对克罗恩病有何影响?
Antonie Van Leeuwenhoek. 1983 Jun;49(2):119-24. doi: 10.1007/BF00393669.
2
Effect of selective decontamination of the digestive tract of donor and recipient on the occurrence of murine delayed-type graft-versus-host disease.供体和受体消化道选择性去污对小鼠迟发型移植物抗宿主病发生的影响。
Med Microbiol Immunol. 1988;177(3):133-44. doi: 10.1007/BF00232893.
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Successive changes of the cellular composition in lymphoid organs of MRL-Mp/lpr-lpr mice during the development of lymphoproliferative disease as investigated in cryosections.通过冷冻切片研究MRL-Mp/lpr-lpr小鼠淋巴增生性疾病发展过程中淋巴器官细胞组成的连续变化。
Clin Immunol Immunopathol. 1988 Mar;46(3):421-31. doi: 10.1016/0090-1229(88)90061-x.
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Fluorescence-activated cell sorter analysis of binding by lipopolysaccharide-specific monoclonal antibodies to gram-negative bacteria.
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Morphometrical parameters of gut microflora in human volunteers.人类志愿者肠道微生物群的形态计量学参数。
Epidemiol Infect. 1991 Oct;107(2):383-91. doi: 10.1017/s0950268800049025.
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Objective quantitation of serum antibody titres against Enterobacteriaceae using indirect immunofluorescence, read by videocamera and image processing system.
Med Microbiol Immunol. 1991;180(2):93-100. doi: 10.1007/BF00193850.
7
Healthy individuals and patients with systemic lupus erythematosus have unique, person-specific spectra of antibodies detectable on immunoblots.健康个体和系统性红斑狼疮患者在免疫印迹上可检测到独特的、因人而异的抗体谱。
Clin Immunol Immunopathol. 1991 Apr;59(1):129-38. doi: 10.1016/0090-1229(91)90087-q.
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Microbial ecology of the gastrointestinal tract.胃肠道的微生物生态学
Annu Rev Microbiol. 1977;31:107-33. doi: 10.1146/annurev.mi.31.100177.000543.

通过免疫形态测定法评估针对粪便细菌的循环抗体:结合定量免疫荧光和图像分析。

Circulating antibodies against faecal bacteria assessed by immunomorphometry: combining quantitative immunofluorescence and image analysis.

作者信息

Apperloo-Renkema H Z, Wilkinson M H, van der Waaij D

机构信息

Laboratory for Medical Microbiology, State University Groningen, The Netherlands.

出版信息

Epidemiol Infect. 1992 Dec;109(3):497-506. doi: 10.1017/s0950268800050494.

DOI:10.1017/s0950268800050494
PMID:1468534
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2271941/
Abstract

A new technique to study the prevalence of circulating antibodies directed against different morphological groups ('morphotypes') of bacteria in fresh faeces is presented. The technique combines quantitative indirect immunofluorescence with digital image analysis. Plasma antibody titres and patterns of IgA, IgG and IgM isotype against morphotypes of faecal bacteria were determined in ten healthy individuals.

摘要

本文介绍了一种研究新鲜粪便中针对不同形态学组(“形态型”)细菌的循环抗体流行情况的新技术。该技术将定量间接免疫荧光与数字图像分析相结合。在10名健康个体中测定了针对粪便细菌形态型的血浆抗体滴度以及IgA、IgG和IgM同种型的模式。