自动板层治疗性角膜移植术（ALTK）治疗角膜基质前至中部病变

Automated lamellar therapeutic keratoplasty (ALTK) in the treatment of anterior to mid-stromal corneal pathologies.

作者信息

Vajpayee Rasik B, Vasudendra Nagaraj, Titiyal Jeewan S, Tandon Radhika, Sharma Namrata, Sinha Rajesh

机构信息

Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Science, New Delhi, India.

出版信息

Acta Ophthalmol Scand. 2006 Dec;84(6):771-3. doi: 10.1111/j.1600-0420.2006.00722.x.

DOI:10.1111/j.1600-0420.2006.00722.x

PMID:17083536

Abstract

PURPOSE

To evaluate the efficacy of automated lamellar therapeutic keratoplasty (ALTK) in the treatment of anterior to mid-stromal corneal pathologies.

METHODS

A prospective clinical study was undertaken in 15 eyes of 15 patients who underwent ALTK using the ALTK System (Moria/Microtek Inc., Doylestown, Pennsylvania, USA). The parameters evaluated were uncorrected and best corrected visual acuity (BCVA), keratometry, pachymetry, contrast sensitivity, glare acuity, intraoperative surgical time and complications, postoperative time to epithelialization, graft clarity and postoperative complications.

RESULTS

The mean surgical time was 46 +/- 9 mins. The BCVA, contrast sensitivity and glare acuity significantly improved at 6 months postoperatively. The mean decimal BCVA was 0.08 +/- 0.03 preoperatively, which improved to 0.33 +/- 0.30 at 6 months, when 11 eyes had BCVA > or = 6/18. The median epithelialization time was 3 days (range 1-10 days).

CONCLUSIONS

Automated lamellar therapeutic keratoplasty appears to be safe and effective for diseases affecting the anterior to mid-stroma of the cornea.

摘要

目的

评估自动板层治疗性角膜移植术（ALTK）治疗角膜前基质至中基质病变的疗效。

方法

对15例患者的15只眼进行前瞻性临床研究，这些患者使用ALTK系统（美国宾夕法尼亚州多伊尔斯顿的Moria/Microtek公司）接受了ALTK治疗。评估的参数包括未矫正和最佳矫正视力（BCVA）、角膜曲率测量、角膜厚度测量、对比敏感度、眩光视力、术中手术时间及并发症、术后上皮化时间、植片清晰度和术后并发症。