Yager Julie A, Hutchison Lisa, Barrett John W
Yager-Best Veterinary Surgical Pathology, Guelph, Ontario, Canada.
Vet Dermatol. 2006 Dec;17(6):443-8. doi: 10.1111/j.1365-3164.2006.00553.x.
Poxvirus infections affecting the skin of cats are extremely rare in North America, in contrast to Europe where cowpox virus is well recognized as an accidental pathogen in cats that hunt small rodents. The virus or viruses responsible for the anecdotal cases in North America have never been characterized. This paper reports a case of raccoonpox infection in a Canadian cat. Biopsy of the initial ulcerative lesion on the forepaw revealed ballooning degeneration of surface and follicular keratinoctyes. Infected cells contained large eosinophilic type A inclusions. Electron microscopic examination revealed virions of an orthopoxvirus, subsequently identified as raccoonpox by polymerase chain reaction and gene sequencing. The cat made a full recovery.
在北美，影响猫皮肤的痘病毒感染极为罕见，而在欧洲，牛痘病毒被公认为是捕食小型啮齿动物的猫的偶然病原体。导致北美这些传闻病例的病毒从未被鉴定过。本文报告了一例加拿大猫感染浣熊痘的病例。对前爪最初的溃疡性病变进行活检，发现表面和毛囊角质形成细胞出现气球样变性。受感染的细胞含有大型嗜酸性A 型包涵体。电子显微镜检查发现正痘病毒的病毒粒子，随后通过聚合酶链反应和基因测序鉴定为浣熊痘病毒。这只猫完全康复了。
