Hutchinson B R, Newson A J
Anaesth Intensive Care. 1975 Aug;3(3):198-203. doi: 10.1177/0310057X7500300304.
The incidence of Mendelson's syndrome in the four major Auckland hospitals is reviewed. The frequency of this condition was reduced following the pre-operative administration of magnesium trisilicate mixture in two hospitals. A trial was conducted in a third hospital and this showed that a 52 per cent incidence of highly acid gastric juice (pH less than 2.5) in patients prepared for elective surgery was reduced by administration of magnesium trisilicate mixture at the time of premedication. When the magnesium trisilicate mixture was given within the 30 minutes prior to induction of anaesthesia, the number of patients with highly acid gastric content fell to one per cent.
对奥克兰四大医院门德尔松综合征的发病率进行了回顾。在两家医院，术前服用三硅酸镁合剂后，这种病症的发生率有所降低。在第三家医院进行了一项试验，结果表明，在择期手术患者术前用药时给予三硅酸镁合剂，可降低高酸性胃液（pH值小于2.5）发生率52%。在诱导麻醉前30分钟内给予三硅酸镁合剂时，高酸性胃内容物患者数量降至1%。
