Hutchinson B R
Anaesth Intensive Care. 1976 Aug;4(3):192-5. doi: 10.1177/0310057X7600400303.
Three groups, each of forty children aged less than five years and prepared for elective surgery, had their gastric contents' volume and pH measured. The control group showed an incidence of 67-5 per cent with high acidity (pH equal to or less than 2-5). In the second and third groups magnesium trisilicate mixture was given within thirty minutes prior to induction of anaesthesia. The second group, sampled after induction of anaesthesia, showed a marked reduction in acidity, while the third group, sampled at the termination of anaesthesia and surgery, demonstrated that in most cases the neutralization of gastric acidity was still effective.
三组，每组四十名五岁以下准备接受择期手术的儿童，测量了他们胃内容物的体积和pH值。对照组高酸度（pH等于或小于2.5）的发生率为67.5%。在第二组和第三组中，在麻醉诱导前三十分钟内给予三硅酸镁混合物。第二组在麻醉诱导后取样，酸度明显降低，而第三组在麻醉和手术结束时取样，结果表明在大多数情况下胃酸中和仍然有效。
