巴西圣保罗空气污染水平上升，人类和小鼠的雄性与雌性比例下降。
Increased levels of air pollution and a decrease in the human and mouse male-to-female ratio in São Paulo, Brazil.
作者信息
Lichtenfels Ana Julia F C, Gomes Joabner B, Pieri Patrícia C, El Khouri Miraglia Simone G, Hallak Jorge, Saldiva Paulo H N
机构信息
Department of Pathology, University of São Paulo, São Paulo, Brazil.
出版信息
Fertil Steril. 2007 Jan;87(1):230-2. doi: 10.1016/j.fertnstert.2006.06.023. Epub 2006 Nov 2.
A significant negative association (R(2) = 0.7642; P=.013) between particulate matter and secondary sex ratio was found when evaluating people in the city of São Paulo, Brazil. An animal model with male mice raised in nonfiltered open-top chambers showed a significant reduction in the secondary sex ratio (P=.041), suggesting that ambient air pollution may interfere with sex distribution by altering the X:Y sperm proportion in pollution-exposed males.
在评估巴西圣保罗市的人群时，发现颗粒物与第二性征比例之间存在显著的负相关关系（R(2) = 0.7642；P = 0.013）。在未过滤的开放式顶部舱室中饲养雄性小鼠的动物模型显示，第二性征比例显著降低（P = 0.041），这表明环境空气污染可能通过改变暴露于污染环境中的雄性的X:Y精子比例来干扰性别分布。
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