Yamataki A, Chiba Y, Tokoro K, Ide K, Yagishita S, Wakabayashi Y, Kan S
Department of Neurosurgery, Kanagawa Rehabilitation Center, Japan.
Neurol Med Chir (Tokyo). 1990 Oct;30(10):759-62. doi: 10.2176/nmc.30.759.
Intracranial fibrous xanthoma is extremely rare; only 11 cases have been reported so far. The authors report a case of multicentric intracranial fibrous xanthoma. Precontrast computed tomographic (CT) scans revealed a left frontal subdural mass, which had previously been diagnosed as a chronic subdural hematoma at another hospital. However, operation disclosed no hematoma but a granulomatous tumor. The biopsied specimen was histologically diagnosed as fibrous xanthoma. Postoperative postcontrast CT scans showed intense homogeneous enhancement at the clival and the left frontal regions, both of which appeared as iso- to low-intensity areas on T1-weighted magnetic resonance (MR) images and as low-intensity areas on T2-weighted MR images. She gradually recovered by conservative treatment but suddenly died of cerebral infarction. Autopsy revealed fibrous xanthomas in the left frontal and the clival regions. This is the first report of the use of MR imaging for intracranial fibrous xanthoma, and its features differ from those of common intracranial parenchymal tumors, MR imaging can be helpful in the diagnosis of this tumor.
颅内纤维性黄色瘤极为罕见；迄今为止仅报道过11例。作者报告了1例多中心性颅内纤维性黄色瘤病例。平扫计算机断层扫描（CT）显示左侧额叶硬膜下肿块，该肿块在另一家医院先前被诊断为慢性硬膜下血肿。然而，手术中未发现血肿，而是一个肉芽肿性肿瘤。活检标本经组织学诊断为纤维性黄色瘤。术后增强CT扫描显示斜坡和左侧额叶区域有明显均匀强化，这两个区域在T1加权磁共振（MR）图像上呈等信号至低信号区，在T2加权MR图像上呈低信号区。她经保守治疗后逐渐康复，但突然死于脑梗死。尸检发现左侧额叶和斜坡区域有纤维性黄色瘤。这是关于颅内纤维性黄色瘤使用MR成像的首次报告，其特征与常见的颅内实质肿瘤不同，MR成像有助于该肿瘤的诊断。
