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患有注意力缺陷/多动障碍的成年人的睡眠与睡眠障碍

Sleep and sleep disorders in adults with attention deficit/hyperactivity disorder.

作者信息

Philipsen Alexandra, Hornyak Magdolna, Riemann Dieter

机构信息

Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Haupt-strasse 5, 79104 Freiburg, Germany.

出版信息

Sleep Med Rev. 2006 Dec;10(6):399-405. doi: 10.1016/j.smrv.2006.05.002. Epub 2006 Nov 3.

Abstract

Attention deficit/hyperactivity disorder (ADHD) is a frequent disorder that often persists in adulthood. Persistent ADHD is known to be a serious risk factor for other disorders in adulthood, and adults with ADHD often report on sleep disorders. Despite this, only few studies have investigated the subjective and objective quality of sleep in adults suffering from ADHD. Previous studies have revealed seriously impaired subjective sleep quality and increased nocturnal motor activity in spite of essentially normal standard polysomnographic parameters in this patient group. However, primary sleep disorders such as sleep apnea syndrome or restless legs syndrome (RLS) may be misdiagnosed as ADHD. Moreover, ADHD and primary sleep disorders may occur as comorbidities. In particular, RLS was suggested to be highly associated with ADHD, indicating a probable common central nervous dopaminergic dysfunction. To date, larger studies with adequate sample sizes that compare sleep in adult patients with ADHD, healthy control groups and patients with other primary sleep disorders are still lacking.

摘要

注意缺陷多动障碍(ADHD)是一种常见的疾病,常持续至成年期。持续性ADHD是成年期其他疾病的严重风险因素,患有ADHD的成年人常报告存在睡眠障碍。尽管如此,仅有少数研究调查了ADHD成年患者的主观和客观睡眠质量。既往研究显示,该患者群体尽管基本睡眠多导图参数基本正常,但主观睡眠质量严重受损,夜间运动活动增加。然而,诸如睡眠呼吸暂停综合征或不安腿综合征(RLS)等原发性睡眠障碍可能会被误诊为ADHD。此外,ADHD和原发性睡眠障碍可能作为共病出现。特别是,RLS被认为与ADHD高度相关,提示可能存在共同的中枢神经多巴胺能功能障碍。迄今为止,仍缺乏足够样本量的大型研究来比较ADHD成年患者、健康对照组和其他原发性睡眠障碍患者的睡眠情况。

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