• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

针刺疗法对一名正在服用托莫西汀的成年注意力缺陷多动障碍患者自我感知压力及注意力缺陷多动障碍核心症状的影响。一项深入单病例研究的见解

The Impact of Acupuncture on Self-Perceived Stress and ADHD Core Symptomatology in an Adult, Atomoxetine-taking ADHD Participant. Insights from an In-depth Single Case Study.

作者信息

May Nils, Bennett Ashley

机构信息

Northern College of Acupuncture, York, United Kingdom.

School of Psychology, University of Bedfordshire, Luton, United Kingdom.

出版信息

Integr Med (Encinitas). 2023 Jul;22(3):28-36.

PMID:37534023
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10393382/
Abstract

BACKGROUND

Attention Deficit Hyperactivity Disorder (ADHD) includes inattention, hyperactivity, and impulsivity as core symptoms and is associated with increased self-perceived stress.

PRIMARY STUDY OBJECTIVE

This article evaluates the impact of acupuncture (provided in addition to regular pharmacological treatment with Atomoxetine) on self-perceived stress and ADHD core symptomatology, compared to atomoxetine (ATX) alone.

METHODS/DESIGN: In-depth single case study, involving a mixed methods approach with questionnaires and interviews was used. The participant completed two rating scales. Additionally, semi-structured interviews were held. Qualitative data were subjected to content analysis and both sets of data were triangulated.

SETTING

Data collection/intervention (treatments) took place at an Acupuncture clinic in Hamburg, Germany, EU.

PARTICIPANTS

One adult, atomoxetine-taking ADHD participant.

INTERVENTION

Acupuncture according to Chinese medicine-diagnosis twice/week, over the course of eight weeks, following a pre-defined but flexible point protocol.

PRIMARY OUTCOME MEASURES

  1. The Current Symptom Scale (CSS) and the Perceived Stress Scale (PSS). 2) Semi-structured interviews.

RESULTS

Acupuncture treatments in addition to regular ATX intake positively affected the participant's ADHD symptoms (PSS - 31%, total score of the CSS - 47%). There was a considerable decrease in subgroup scores (attention deficit - 39%; functionality impairment - 55%; hyperactivity/impulsivity - 53%; impulsivity - 30%). Post-interventional interviews showed perceived increased self-control, (self-) awareness and centeredness. Combined treatment was perceived as more beneficial than pharmaceutical treatment alone.

CONCLUSION

Acupuncture treatment appears to have a positive impact on both self-perception of stress and ADHD core symptomatology. Findings were partially congruent with the reviewed research literature but due to limitations/risks of bias (ROBs) associated with the design, no concrete conclusions regarding a potential method-related specificity can be drawn. Further research with larger samples and a more robust design is recommended.

摘要

背景

注意力缺陷多动障碍(ADHD)以注意力不集中、多动和冲动为核心症状,且与自我感知压力增加有关。

主要研究目的

本文评估与单独使用托莫西汀(ATX)相比,针刺疗法(在使用托莫西汀进行常规药物治疗的基础上)对自我感知压力和ADHD核心症状的影响。

方法/设计:采用深入的单病例研究,涉及问卷调查和访谈的混合方法。参与者完成了两个评定量表。此外,还进行了半结构化访谈。对定性数据进行了内容分析,并对两组数据进行了三角互证。

地点

数据收集/干预(治疗)在欧盟德国汉堡的一家针灸诊所进行。

参与者

一名正在服用托莫西汀的成年ADHD患者。

干预措施

根据中医诊断进行针刺治疗,每周两次,共八周,遵循预先定义但灵活的穴位方案。

主要结局指标

1)当前症状量表(CSS)和感知压力量表(PSS)。2)半结构化访谈。

结果

在常规服用ATX的基础上进行针刺治疗对参与者的ADHD症状产生了积极影响(PSS降低31%,CSS总分降低47%)。各亚组得分有显著下降(注意力缺陷降低39%;功能损害降低55%;多动/冲动降低53%;冲动降低30%)。干预后的访谈显示,参与者自我控制、(自我)意识和专注力有所增强。联合治疗被认为比单纯药物治疗更有益。

结论

针刺治疗似乎对压力的自我感知和ADHD核心症状均有积极影响。研究结果与已审查的研究文献部分一致,但由于该设计存在局限性/偏倚风险,无法就潜在的方法特异性得出具体结论。建议开展更大样本量和更严谨设计的进一步研究。

相似文献

1
The Impact of Acupuncture on Self-Perceived Stress and ADHD Core Symptomatology in an Adult, Atomoxetine-taking ADHD Participant. Insights from an In-depth Single Case Study.针刺疗法对一名正在服用托莫西汀的成年注意力缺陷多动障碍患者自我感知压力及注意力缺陷多动障碍核心症状的影响。一项深入单病例研究的见解
Integr Med (Encinitas). 2023 Jul;22(3):28-36.
2
Extended-Release Viloxazine Compared with Atomoxetine for Attention Deficit Hyperactivity Disorder.缓释维洛沙嗪与托莫西汀治疗注意缺陷多动障碍的比较。
CNS Drugs. 2023 Jul;37(7):655-660. doi: 10.1007/s40263-023-01023-6. Epub 2023 Jul 10.
3
An Open-Label, Randomized Trial of Methylphenidate and Atomoxetine Treatment in Children with Attention-Deficit/Hyperactivity Disorder.一项关于哌甲酯和托莫西汀治疗注意缺陷/多动障碍儿童的开放标签随机试验。
J Child Adolesc Psychopharmacol. 2015 Sep;25(7):566-73. doi: 10.1089/cap.2015.0035. Epub 2015 Jul 29.
4
Relationships Between Functional Outcomes and Symptomatic Improvement in Atomoxetine-Treated Adult Patients with Attention-Deficit/Hyperactivity Disorder: Post Hoc Analysis of an Integrated Database.托莫西汀治疗成人注意缺陷/多动障碍患者的功能结局与症状改善之间的关系:综合数据库的事后分析
CNS Drugs. 2016 Jun;30(6):541-58. doi: 10.1007/s40263-016-0346-3.
5
Comparative efficacy of guanfacine extended release versus atomoxetine for the treatment of attention-deficit/hyperactivity disorder in children and adolescents: applying matching-adjusted indirect comparison methodology.胍法辛缓释剂与托莫西汀治疗儿童和青少年注意缺陷多动障碍的疗效比较:应用匹配调整间接比较法。
CNS Drugs. 2013 Nov;27(11):943-53. doi: 10.1007/s40263-013-0102-x.
6
Health-related quality of life in children and adolescents who have a diagnosis of attention-deficit/hyperactivity disorder.患有注意力缺陷/多动障碍的儿童和青少年的健康相关生活质量。
Pediatrics. 2004 Nov;114(5):e541-7. doi: 10.1542/peds.2004-0844.
7
Once-daily atomoxetine treatment for children with attention-deficit/hyperactivity disorder, including an assessment of evening and morning behavior: a double-blind, placebo-controlled trial.一日一次服用托莫西汀治疗注意缺陷/多动障碍儿童,包括对早晚行为的评估:一项双盲、安慰剂对照试验。
Pediatrics. 2004 Jul;114(1):e1-8. doi: 10.1542/peds.114.1.e1.
8
Effects of Atomoxetine in Individuals with Attention-Deficit/Hyperactivity Disorder and Low-Functioning Autism Spectrum Disorder.托莫西汀对注意力缺陷/多动障碍和低功能自闭症谱系障碍患者的影响。
J Child Adolesc Psychopharmacol. 2016 Nov;26(9):798-806. doi: 10.1089/cap.2015.0179. Epub 2016 May 26.
9
Atomoxetine treatment in adults with attention-deficit/hyperactivity disorder.成人注意力缺陷/多动障碍的托莫西汀治疗
Postgrad Med. 2015;127(7):686-701. doi: 10.1080/00325481.2015.1081046.
10
Atomoxetine improved attention in children and adolescents with attention-deficit/hyperactivity disorder and dyslexia in a 16 week, acute, randomized, double-blind trial.在一项为期16周的急性、随机、双盲试验中,托莫西汀改善了患有注意力缺陷多动障碍和阅读障碍的儿童及青少年的注意力。
J Child Adolesc Psychopharmacol. 2013 Nov;23(9):605-13. doi: 10.1089/cap.2013.0054. Epub 2013 Nov 9.

本文引用的文献

1
Complementary and Alternative Medicine Use by ADHD Patients: A Systematic Review.ADHD 患者的补充和替代医学使用:系统评价。
J Atten Disord. 2022 Dec;26(14):1833-1845. doi: 10.1177/10870547221111557. Epub 2022 Jul 26.
2
Genetics of attention deficit hyperactivity disorder.注意缺陷多动障碍的遗传学。
Mol Psychiatry. 2019 Apr;24(4):562-575. doi: 10.1038/s41380-018-0070-0. Epub 2018 Jun 11.
3
A critical appraisal of atomoxetine in the management of ADHD.对托莫西汀治疗注意缺陷多动障碍的批判性评价。
Ther Clin Risk Manag. 2015 Dec 23;12:27-39. doi: 10.2147/TCRM.S59270. eCollection 2016.
4
Repeated verum but not placebo acupuncture normalizes connectivity in brain regions dysregulated in chronic pain.重复进行真针灸而非假针灸可使慢性疼痛中失调的脑区连接恢复正常。
Neuroimage Clin. 2015 Sep 25;9:430-5. doi: 10.1016/j.nicl.2015.09.012. eCollection 2015.
5
Different Placebos, Different Mechanisms, Different Outcomes: Lessons for Clinical Trials.不同的安慰剂、不同的机制、不同的结果:临床试验的经验教训
PLoS One. 2015 Nov 4;10(11):e0140967. doi: 10.1371/journal.pone.0140967. eCollection 2015.
6
Long-Term Pharmacotherapy of Adults With Attention Deficit Hyperactivity Disorder: A Literature Review and Clinical Study.成人注意力缺陷多动障碍的长期药物治疗:文献综述与临床研究
Basic Clin Pharmacol Toxicol. 2016 Jan;118(1):23-31. doi: 10.1111/bcpt.12477. Epub 2015 Sep 24.
7
Traditional Chinese medicine in the treatment of ADHD: a review.中医治疗注意缺陷多动障碍:综述
Child Adolesc Psychiatr Clin N Am. 2014 Oct;23(4):853-81. doi: 10.1016/j.chc.2014.05.011.
8
Bias in research.研究中的偏倚
Evid Based Nurs. 2014 Oct;17(4):100-1. doi: 10.1136/eb-2014-101946. Epub 2014 Aug 5.
9
Review of the psychometric evidence of the perceived stress scale.压力知觉量表的心理计量学证据回顾。
Asian Nurs Res (Korean Soc Nurs Sci). 2012 Dec;6(4):121-7. doi: 10.1016/j.anr.2012.08.004. Epub 2012 Sep 18.
10
Biology of purinergic signalling: its ancient evolutionary roots, its omnipresence and its multiple functional significance.嘌呤能信号传导的生物学:其古老的进化根源、无所不在的特性及其多重功能意义。
Bioessays. 2014 Jul;36(7):697-705. doi: 10.1002/bies.201400024. Epub 2014 Apr 30.