Zagami A S, Lambert G A
Institute of Neurological Sciences, Prince Henry Hospital, Sydney, Australia.
Neurosci Lett. 1991 Jan 2;121(1-2):187-90. doi: 10.1016/0304-3940(91)90681-i.
In cats anaesthetized with alpha-chloralose and urethane, extracellular recordings were made in ventrobasal thalamus from cells responding to electrical stimulation of the superior sagittal sinus and middle meningeal artery. Capsaicin, but not vehicle, evoked an increase in the firing rate of nociceptive cells (5 of 6 wide dynamic range and the only nociceptive specific cell). Non-nociceptive cells did not respond to either capsaicin or vehicle. Cells with long latencies to electrical stimulation were excited by capsaicin but cells with short latencies were not. Capsaicin-responsive cells were found in the ventroposteromedial nucleus and the medial nucleus of the posterior complex and mostly had receptive fields involving the first trigeminal division.
在用α-氯醛糖和乌拉坦麻醉的猫中，在腹侧基底丘脑对响应上矢状窦和脑膜中动脉电刺激的细胞进行细胞外记录。辣椒素而非赋形剂能诱发伤害性感受细胞（6个宽动态范围细胞中的5个以及唯一的伤害性感受特异性细胞）放电率增加。非伤害性感受细胞对辣椒素和赋形剂均无反应。对电刺激潜伏期长的细胞被辣椒素兴奋，但潜伏期短的细胞则不然。在腹后内侧核和后复合体内侧核中发现了对辣椒素有反应的细胞，且大多数细胞的感受野涉及三叉神经第一分支。
