Zagami A S, Lambert G A
Institute of Neurological Sciences, Prince Henry Hospital, University of New South Wales, Sydney, Australia.
Exp Brain Res. 1990;81(3):552-66. doi: 10.1007/BF02423504.
Extracellular recordings were made in the thalamus of cats anaesthetized with chloralose and urethane following electrical, mechanical and chemical stimulation of the superior sagittal sinus or middle meningeal artery. Facial receptive fields were looked for using electrical and mechanical stimuli. The locations of fifty-six cells were verified histologically. Twenty six cells were located in the ventroposteromedial nucleus (VPM) and six in its ventral periphery (VPMvp). All units in VPM had facial receptive fields, usually involving the first trigeminal division. Cells with nociceptive receptive fields or responding to the craniovascular application of bradykinin were often found in the periphery or "shell" region of VPM. Other craniovascular nociceptive cells were found in VPMvp, in the posterior group and in the intralaminar complex. This study shows that craniovascular afferents in the cat project to several thalamic nuclei and implicate VPM especially in craniovascular nociception.
在用氯醛糖和乌拉坦麻醉的猫的丘脑进行细胞外记录，记录在对大脑上矢状窦或脑膜中动脉进行电、机械和化学刺激之后。使用电刺激和机械刺激寻找面部感受野。通过组织学方法确定了56个细胞的位置。26个细胞位于腹后内侧核（VPM），6个位于其腹侧周边（VPMvp）。VPM中的所有神经元都有面部感受野，通常涉及三叉神经第一分支。在VPM的周边或“壳”区经常发现具有伤害性感受野或对颅血管应用缓激肽有反应的细胞。在VPMvp、后组和板内核复合体中发现了其他颅血管伤害性细胞。这项研究表明，猫的颅血管传入纤维投射到几个丘脑核，尤其涉及VPM在颅血管伤害感受中的作用。
