RNA 5-甲基尿苷甲基转移酶和假尿苷合酶对底物的识别：结构视角 - Suppr

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Substrate recognition by RNA 5-methyluridine methyltransferases and pseudouridine synthases: a structural perspective.

作者信息

Hur Sun, Stroud Robert M, Finer-Moore Janet

机构信息

Department of Biochemistry and Biophysics, University of California, San Francisco, California 94143, USA.

出版信息

J Biol Chem. 2006 Dec 22;281(51):38969-73. doi: 10.1074/jbc.R600034200. Epub 2006 Nov 3.

DOI:10.1074/jbc.R600034200

PMID:17085441

Abstract

摘要

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Substrate recognition by RNA 5-methyluridine methyltransferases and pseudouridine synthases: a structural perspective.

作者信息

Hur Sun, Stroud Robert M, Finer-Moore Janet

机构信息

Department of Biochemistry and Biophysics, University of California, San Francisco, California 94143, USA.

出版信息

J Biol Chem. 2006 Dec 22;281(51):38969-73. doi: 10.1074/jbc.R600034200. Epub 2006 Nov 3.

DOI:10.1074/jbc.R600034200

PMID:17085441

Abstract

摘要

相似文献

Substrate recognition by RNA 5-methyluridine methyltransferases and pseudouridine synthases: a structural perspective.

J Biol Chem. 2006 Dec 22;281(51):38969-73. doi: 10.1074/jbc.R600034200. Epub 2006 Nov 3.

X-ray structure of tRNA pseudouridine synthase TruD reveals an inserted domain with a novel fold.

FEBS Lett. 2004 May 7;565(1-3):59-64. doi: 10.1016/j.febslet.2004.03.085.

RNA-modifying enzymes.

Curr Opin Struct Biol. 2003 Feb;13(1):49-55. doi: 10.1016/s0959-440x(02)00002-7.

Expression, purification, crystallization and preliminary diffraction studies of the tRNA pseudouridine synthase TruD from Escherichia coli.

Acta Crystallogr D Biol Crystallogr. 2004 Apr;60(Pt 4):775-6. doi: 10.1107/S0907444904003506. Epub 2004 Mar 23.

Crystal structure of pseudouridine synthase RluA: indirect sequence readout through protein-induced RNA structure.

Mol Cell. 2006 Nov 17;24(4):535-45. doi: 10.1016/j.molcel.2006.09.017.

The structural basis for tRNA recognition and pseudouridine formation by pseudouridine synthase I.

Nat Struct Biol. 2000 Jan;7(1):23-7. doi: 10.1038/71219.

Structure of a TrmA-RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m5U methyltransferases.

Proc Natl Acad Sci U S A. 2008 May 13;105(19):6876-81. doi: 10.1073/pnas.0802247105. Epub 2008 May 1.

Major identity determinants for enzymatic formation of ribothymidine and pseudouridine in the T psi-loop of yeast tRNAs.

J Mol Biol. 1997 Dec 12;274(4):505-18. doi: 10.1006/jmbi.1997.1417.

Loss of tRNA 5-methyluridine methyltransferase and pseudouridine synthetase activities in 5-fluorouracil and 1-(tetrahydro-2-furanyl)-5-fluorouracil (ftorafur)-treated Escherichia coli.

Biochim Biophys Acta. 1982 Apr 26;697(1):31-40. doi: 10.1016/0167-4781(82)90042-2.

tRNA recognition by a bacterial tRNA Xm32 modification enzyme from the SPOUT methyltransferase superfamily.

Nucleic Acids Res. 2015 Sep 3;43(15):7489-503. doi: 10.1093/nar/gkv745. Epub 2015 Jul 21.

引用本文的文献

Conserved 5-methyluridine tRNA modification modulates ribosome translocation.

Proc Natl Acad Sci U S A. 2024 Aug 27;121(35):e2401743121. doi: 10.1073/pnas.2401743121. Epub 2024 Aug 19.

RNA methylation-related inhibitors: Biological basis and therapeutic potential for cancer therapy.

Clin Transl Med. 2024 Apr;14(4):e1644. doi: 10.1002/ctm2.1644.

Translational Regulation by eIFs and RNA Modifications in Cancer.

Genes (Basel). 2022 Nov 6;13(11):2050. doi: 10.3390/genes13112050.

The role of RNA modification in hepatocellular carcinoma.

Front Pharmacol. 2022 Sep 2;13:984453. doi: 10.3389/fphar.2022.984453. eCollection 2022.

The Role of RNA Modification in HIV-1 Infection.

Int J Mol Sci. 2022 Jul 8;23(14):7571. doi: 10.3390/ijms23147571.

Role of main RNA modifications in cancer: N-methyladenosine, 5-methylcytosine, and pseudouridine.

Signal Transduct Target Ther. 2022 Apr 28;7(1):142. doi: 10.1038/s41392-022-01003-0.

Chemical tagging for sensitive determination of uridine modifications in RNA.

Chem Sci. 2020 Jan 8;11(7):1878-1891. doi: 10.1039/c9sc05094a.

Post-Transcriptional Modifications of Conserved Nucleotides in the T-Loop of tRNA: A Tale of Functional Convergent Evolution.

Genes (Basel). 2021 Jan 22;12(2):140. doi: 10.3390/genes12020140.

The role of mA, mC and Ψ RNA modifications in cancer: Novel therapeutic opportunities.

Mol Cancer. 2021 Jan 18;20(1):18. doi: 10.1186/s12943-020-01263-w.

Naturally occurring modified ribonucleosides.

Wiley Interdiscip Rev RNA. 2020 Sep;11(5):e1595. doi: 10.1002/wrna.1595. Epub 2020 Apr 16.