Sanderson M C, Davis L R, Mowat A P
Arch Dis Child. 1975 Jul;50(7):526-31. doi: 10.1136/adc.50.7.526.
Of 58 children with suspected malabsorption, 27 were shown to have subtotal or partial atrophy, and 31 had normal mucosal histology. Oral glucose tolerance tests, faecal fat excretion, D-xylose excretion tests, Prosparol absorption studies, haematological investigations, and radiological examination of the small bowel failed to distinguish these two groups and frequently gave misleading results. It is concluded that in suspected coeliac disease small intestinal biopsy should be performed as a primary investigation.
在58名疑似吸收不良的儿童中，27名显示有小肠部分或完全萎缩，31名黏膜组织学正常。口服葡萄糖耐量试验、粪便脂肪排泄、D-木糖排泄试验、普罗沙尔吸收研究、血液学检查以及小肠放射学检查均无法区分这两组儿童，且常常得出误导性结果。得出的结论是，在疑似乳糜泻的情况下，应将小肠活检作为首要检查手段。
