实验室检查和影像学研究未能预测空肠黏膜萎缩。
Failure of laboratory and radiological studies to predict jejunal mucosal atrophy.
作者信息
Sanderson M C, Davis L R, Mowat A P
出版信息
Arch Dis Child. 1975 Jul;50(7):526-31. doi: 10.1136/adc.50.7.526.
Abstract
Of 58 children with suspected malabsorption, 27 were shown to have subtotal or partial atrophy, and 31 had normal mucosal histology. Oral glucose tolerance tests, faecal fat excretion, D-xylose excretion tests, Prosparol absorption studies, haematological investigations, and radiological examination of the small bowel failed to distinguish these two groups and frequently gave misleading results. It is concluded that in suspected coeliac disease small intestinal biopsy should be performed as a primary investigation.
摘要
在58名疑似吸收不良的儿童中，27名显示有小肠部分或完全萎缩，31名黏膜组织学正常。口服葡萄糖耐量试验、粪便脂肪排泄、D-木糖排泄试验、普罗沙尔吸收研究、血液学检查以及小肠放射学检查均无法区分这两组儿童，且常常得出误导性结果。得出的结论是，在疑似乳糜泻的情况下，应将小肠活检作为首要检查手段。
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Failure of laboratory and radiological studies to predict jejunal mucosal atrophy.实验室检查和影像学研究未能预测空肠黏膜萎缩。
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本文引用的文献
1
Histopathologic studies in steatorrhea.脂肪痢的组织病理学研究。
Gastroenterology. 1960 Mar;38:419-40.
2
THE D-XYLOSE EXCRETION TEST IN COELIAC DISEASE IN CHILDHOOD.儿童乳糜泻的D-木糖排泄试验
Arch Dis Child. 1963 Oct;38(201):476-80. doi: 10.1136/adc.38.201.476.
3
Duodeno-jejunal biopsy in the investigation of children with coeliac disease.十二指肠空肠活检在乳糜泻患儿检查中的应用
Q J Med. 1962 Jan;31:125-40.
4
Small intestine peroral biopsy in coeliac children.乳糜泻患儿的小肠经口活检
Gut. 1966 Oct;7(5):481-9. doi: 10.1136/gut.7.5.481.
5
Active coeliac disease in childhood. Clinical and laboratory findings of forty-two cases.儿童活动性乳糜泻。42例临床及实验室检查结果
Q J Med. 1969 Apr;38(150):135-58.
6
Jejunal biopsy in celiac disease.乳糜泻的空肠活检
Clin Pediatr (Phila). 1968 Sep;7(9):544-52. doi: 10.1177/000992286800700910.
7
Intestinal malabsorption: a clinical study of 22 children over 2 years of age.肠道吸收不良：22名2岁以上儿童的临床研究
Acta Paediatr Scand. 1970 May;59(3):273-80. doi: 10.1111/j.1651-2227.1970.tb09003.x.
8
Intestinal malabsorption in childhood.儿童期肠道吸收不良
Arch Dis Child. 1966 Dec;41(220):571-96. doi: 10.1136/adc.41.220.571.
9
Food antibodies in serum--a screening test for coeliac disease.血清中的食物抗体——乳糜泻的筛查试验。
Arch Dis Child. 1972 Aug;47(254):594-6. doi: 10.1136/adc.47.254.594.
10
Coeliac disease. Some still controversial aspects.乳糜泻。一些仍存在争议的方面。
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