Ishiwata Toshiji, Koyama Ryo, Homma Noriyuki, Fujii Mitsuhiro, Iwakami Naoko, Nakao Yuta, Iwakami Shin-ichiro, Takahashi Kazuhisa
Department of Respiratory Medicine, Juntendo University School of Medicine.
Nihon Kokyuki Gakkai Zasshi. 2006 Oct;44(10):749-53.
A 28-year-old man complaining of myiodesopsia was given a diagnosis of uveitis. Subsequently he complained facial nerve palsy and enlargement of parotid gland. Heerfordt's syndrome was diagnosed based on the results of several examinations. Facial nerve palsy, enlargement of the parotid gland and uveitis were improved by systemic corticosteroid therapy. At present he is receiving systemic corticosteroid therapy, but numbness in the mouth, thought to be the involvement of the trigeminal nerve, remains. Systemic corticosteroid therapy is usually effective for most cases with Heerford's syndrome. On the other hand, there are some cases with the prolonged peripheral nerve involvement despite systemic corticosteroid therapy, as seen in this case. If peripheral nerve involvement is prolonged, it is necessary to consider small-fibre neuropathy as one possible cause.
一名28岁男性因主诉视物模糊被诊断为葡萄膜炎。随后,他又出现面神经麻痹和腮腺肿大。根据多项检查结果诊断为黑福特综合征。全身应用皮质类固醇治疗后,面神经麻痹、腮腺肿大和葡萄膜炎均有所改善。目前他正在接受全身皮质类固醇治疗,但口腔麻木(被认为是三叉神经受累)仍然存在。全身皮质类固醇治疗通常对大多数黑福特综合征病例有效。另一方面,尽管进行了全身皮质类固醇治疗,仍有一些病例存在周围神经受累时间延长的情况,本病例就是如此。如果周围神经受累时间延长,有必要考虑小纤维神经病变作为一种可能的原因。