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[赫福特综合征未经皮质类固醇治疗而缓解]

[Heerfordt's syndrome remitting without corticosteroid therapy].

作者信息

Itoh T, Tanaka R, Matsushita H

机构信息

Department of Internal Medicine, Municipal Hospital, Osaka, Japan.

出版信息

Nihon Kokyuki Gakkai Zasshi. 1998 May;36(5):494-7.

PMID:9742871
Abstract

A 25-year-old woman presented with low-grade fever, uveitis, and bilateral swelling of the parotid glands. Her older sister had a history of sarcoidosis. A chest X-ray film showed bilateral hilar lymphadenopathy. The low-grade fever persisted after admission. Ga scintigraphy showed abnormal uptake in the parotid glands and hilar lymph nodes bilaterally. Sarcoidosis was diagnosed histologically after epithelioid cell granulomas without caseous necrosis were found in a specimen obtained by transbronchial biopsy. Heerfordt's syndrome was the final diagnosis. Six days after admission, left facial and left trigeminal nerve paralysis developed. The symptoms remitted without steroid therapy and, as of eight months after discharge there had been no evidence of recurrence.

摘要

一名25岁女性出现低热、葡萄膜炎和双侧腮腺肿大。她的姐姐有结节病病史。胸部X线片显示双侧肺门淋巴结肿大。入院后低热持续存在。镓闪烁扫描显示双侧腮腺和肺门淋巴结摄取异常。经支气管活检获得的标本中发现上皮样细胞肉芽肿且无干酪样坏死,组织学诊断为结节病。最终诊断为黑福特综合征。入院6天后,出现左侧面部和左侧三叉神经麻痹。未经类固醇治疗症状缓解,截至出院8个月,无复发迹象。

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