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退伍军人健康管理局中患有和未患有糖尿病的退伍军人抑郁症后续护理不足及其对抗抑郁药治疗时长的影响。

Inadequate follow-up care for depression and its impact on antidepressant treatment duration among veterans with and without diabetes mellitus in the Veterans Health Administration.

作者信息

Jones Laura E, Turvey Carolyn, Carney-Doebbeling Caroline

机构信息

Roudebush VAMC HSR&D Center of Excellence on Implementing Evidence-Based Practice (CIEBP), Indianapolis, IN 46202, USA.

出版信息

Gen Hosp Psychiatry. 2006 Nov-Dec;28(6):465-74. doi: 10.1016/j.genhosppsych.2006.08.002.

DOI:10.1016/j.genhosppsych.2006.08.002
PMID:17088161
Abstract

OBJECTIVE

Our objective was to describe the adequacy of follow-up care for depression and its association with antidepressant treatment duration among veterans with and without diabetes mellitus (DM).

METHOD

This was a retrospective study (1997-2005) of 2178 veterans (33% with DM) in a Midwestern Veterans Health Administration facility who had a new episode of unipolar depression. Adequate follow-up care was defined by a health care visit within 7 and 14 days, and >/=3 visits following antidepressant treatment initiation. Adequate treatment duration was defined by a medication possession ratio of >/=80%. Multivariate logistic regression was used to calculate odds ratios (ORs) adjusted for demographic, clinical and health care utilization characteristics.

RESULTS

Only 27% received >/=3 follow-up visits within 12 weeks, and <23% received follow-up within 2 weeks of antidepressant initiation. Subjects with DM were 1.36-fold more likely [95% confidence interval (95% CI)=1.05-1.75] to have received >/=3 visits but were similarly likely to have received follow-up within 7 days (OR=1.02; 95% CI=0.74-1.41) or 14 days (OR=1.08; 95% CI=0.83-1.40) of antidepressant initiation. Adequate follow-up care was the most important predictor of adequate treatment duration (OR=2.10; 95% CI=1.54-2.88).

CONCLUSION

DM had little influence on the adequacy of follow-up care for depression, with few exceptions. Follow-up care for depression is underutilized and has a significant impact on antidepressant treatment duration. Strategies to more effectively manage depression treatment are required.

摘要

目的

我们的目的是描述糖尿病(DM)患者和非糖尿病退伍军人抑郁症后续护理的充分性及其与抗抑郁治疗持续时间的关联。

方法

这是一项对中西部退伍军人健康管理机构2178名退伍军人(33%患有DM)进行的回顾性研究(1997 - 2005年),这些退伍军人经历了新发的单相抑郁症。充分的后续护理定义为在7天和14天内进行一次医疗保健就诊,以及在开始抗抑郁治疗后进行≥3次就诊。充分的治疗持续时间定义为药物持有率≥80%。使用多因素逻辑回归来计算经人口统计学、临床和医疗保健利用特征调整后的比值比(OR)。

结果

只有27%的人在12周内接受了≥3次后续就诊,不到23%的人在开始抗抑郁治疗后2周内接受了后续护理。患有DM的受试者接受≥3次就诊的可能性高1.36倍[95%置信区间(95%CI)=1.05 - 1.75],但在开始抗抑郁治疗后7天(OR = 1.02;95%CI = 0.74 - 1.41)或14天(OR = 1.08;95%CI = 0.83 - 1.40)内接受后续护理的可能性相似。充分的后续护理是充分治疗持续时间的最重要预测因素(OR = 2.10;95%CI = 1.54 - 2.88)。

结论

除少数例外情况外,DM对抑郁症后续护理的充分性影响不大。抑郁症的后续护理未得到充分利用,且对抗抑郁治疗持续时间有重大影响。需要采取更有效的策略来管理抑郁症治疗。

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