Faculty of Medicine and Health Sciences, Centre de recherche Charles-Le Moyne, 12370Université de Sherbrooke, Longueuil, Quebec, Canada.
Department of Psychology, Centre de recherche de l'Institut universitaire de gériatrie de Montréal (CRIUGM), 60405Université de Montréal, Montreal, Quebec, Canada.
Can J Psychiatry. 2022 Sep;67(9):669-678. doi: 10.1177/07067437221082883. Epub 2022 Mar 7.
To assess the association between receipt of minimally adequate treatment (MAT) and mortality in a sample of community primary care older adults with depression and anxiety.
The present study was conducted among a sample of 358 older adults ( ≥ 65 years old) with depression or an anxiety disorder recruited in primary care practices between 2011 and 2013. Participants agreed to link their health survey and administrative data for the 3 years preceding and following the baseline interview. Depression and anxiety disorders were based on self-reported symptoms aligned with DSM-5 criteria and physician diagnoses (International Classification of Diseases [ICD], 9 and 10 revisions). MAT was defined according to Canadian guidelines and include receipt of pharmacotherapy and ≥ 4 medical visits within 3 months or a number of psychotherapy sessions (individual, group, or family) over 12 months (depression: ≥8; anxiety disorders: ≥5 to 7). All-cause 3-year mortality was ascertained from the vital statistics death registry in Québec. Propensity score weighted regression analysis was conducted to assess the association between receipt of MAT and mortality adjusting for individual, clinical, and health system study factors.
Receipt of MAT was associated with a reduced risk of mortality (hazard ratio [HR]: 0.27; 95% confidence interval [95% CI], 0.12 to 0.62). Individual and clinical factors associated with increased mortality included older age, male sex, being single, low functional status, and increased physical disorders and cognitive functioning. Lifestyle factors associated with reduced and increased mortality included alcohol consumption and smoking, respectively. Health system factors such as perceived adequate number of visits to speak to the doctor about emotional problems and continuity of care were associated with reduced mortality.
The current study highlights the important role of primary care physicians in detecting and providing MAT for older adults with depression and anxiety, as this may have an effect on longevity.
评估在接受最小充分治疗(MAT)的样本中,社区初级保健老年抑郁症和焦虑症患者的死亡率之间的关联。
本研究是在 2011 年至 2013 年间在初级保健诊所招募的 358 名患有抑郁症或焦虑症的老年患者(≥65 岁)中进行的。参与者同意将他们的健康调查和管理数据与基线访谈前和后 3 年相关联。抑郁和焦虑障碍是基于与 DSM-5 标准和医生诊断(国际疾病分类[ICD],第 9 和 10 版)一致的自我报告症状。MAT 根据加拿大指南定义,包括接受药物治疗和在 3 个月内接受≥4 次医疗就诊,或在 12 个月内接受≥8 次(抑郁症:≥8;焦虑症:≥5 至 7 次)的心理治疗次数(个体、团体或家庭)。全因 3 年死亡率从魁北克生命统计死亡登记处确定。采用倾向评分加权回归分析,在调整个体、临床和卫生系统研究因素的情况下,评估接受 MAT 与死亡率之间的关联。
接受 MAT 与降低死亡率相关(风险比[HR]:0.27;95%置信区间[95%CI]:0.12 至 0.62)。与死亡率增加相关的个体和临床因素包括年龄较大、男性、单身、较低的功能状态以及增加的身体疾病和认知功能。与降低和增加死亡率相关的生活方式因素分别为饮酒和吸烟。与降低死亡率相关的卫生系统因素包括认为有足够的就诊次数与医生讨论情绪问题和连续性护理。
目前的研究强调了初级保健医生在发现和为老年抑郁症和焦虑症患者提供 MAT 方面的重要作用,因为这可能对长寿有影响。