Patten Scott B, Williams Jeanne V A, Esposito Eleonora, Beck Cynthia A
Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Gen Hosp Psychiatry. 2006 Nov-Dec;28(6):503-8. doi: 10.1016/j.genhosppsych.2006.09.001.
Community studies have failed to confirm that biochemically assessed thyroid status is significantly associated with psychopathology. However, it has been reported that self-reported thyroid disease is associated with symptoms of depression and anxiety. The objective of the current study was to determine whether self-reported thyroid disease is associated with elevated mental disorder prevalence in the general population.
Data from the Canadian Community Health Survey (CCHS) 1.2: Mental Health and Well-being were used. The CCHS 1.2 included the World Mental Health version of the Composite International Diagnostic Interview and collected self-report data about professionally diagnosed chronic medical conditions, including thyroid disease.
Twelve-month and lifetime mental disorder prevalence was higher in subjects with thyroid disease than in subjects reporting no chronic conditions. For each condition examined (major depressive disorder, bipolar disorder, panic disorder/agoraphobia and social phobia), the 12-month and lifetime prevalence in subjects with thyroid disease resembled that of an aggregate category of subjects having other chronic conditions. After adjustment for age, sex and other chronic conditions, only social phobia was found to be associated with thyroid disease.
People with thyroid disease are not a particularly high-need group for mental disorder screening or intervention, at least not in the community population.
社区研究未能证实经生化评估的甲状腺状态与精神病理学显著相关。然而,有报道称自我报告的甲状腺疾病与抑郁和焦虑症状有关。本研究的目的是确定自我报告的甲状腺疾病是否与普通人群中精神障碍患病率升高有关。
使用来自加拿大社区健康调查(CCHS)1.2:心理健康与幸福的数据。CCHS 1.2包括世界心理健康版的综合国际诊断访谈,并收集了关于专业诊断的慢性疾病(包括甲状腺疾病)的自我报告数据。
甲状腺疾病患者的12个月和终生精神障碍患病率高于未报告慢性病的患者。对于所检查的每种疾病(重度抑郁症、双相情感障碍、惊恐障碍/广场恐惧症和社交恐惧症),甲状腺疾病患者的12个月和终生患病率与患有其他慢性病的总体人群相似。在对年龄、性别和其他慢性病进行调整后,仅发现社交恐惧症与甲状腺疾病有关。
甲状腺疾病患者并非精神障碍筛查或干预的特别高需求群体,至少在社区人群中不是。