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无畏型与恐惧型惊恐发作:来自全国共病调查的一项普通人群研究。

Non-fearful vs. fearful panic attacks: a general population study from the National Comorbidity Survey.

作者信息

Chen Junwen, Tsuchiya Masao, Kawakami Norito, Furukawa Toshi A

机构信息

Department of Psychiatry and Cognitive-Behavioral Medicine, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, Nagoya, Japan.

出版信息

J Affect Disord. 2009 Jan;112(1-3):273-8. doi: 10.1016/j.jad.2008.04.014. Epub 2008 Jun 4.

Abstract

BACKGROUND

Non-fearful panic attacks constitute a subgroup of panic attacks without the experience of subjective fear. However, previous studies were mostly carried out under medical settings and with small samples. The present study aims to clarify and expand the previous findings including the prevalence and characteristics of non-fearful panic attacks by using the National Comorbidity Survey (NCS) database.

METHODS

From the 8098 original respondents in the NCS, subjects who met the DSM-III-R diagnostic criteria for a lifetime panic attack were selected. Of these, individuals with non-fearful panic attacks were identified and comparisons with subjects with fearful panic attacks were conducted.

RESULTS

30% of panic attacks occur without fears of dying or going crazy. Although these non-fearful panic attacks do not differ from their fearful counterparts in terms of age, age of onset or frequency of attacks, they are less often associated with some symptoms including shortness of breath, trembling, smothering and depersonalization, lead less often to anticipatory anxiety, and lead to less treatment with medication. Although they lead equally to panic disorder diagnosis and cause as much functional impairment, the non-fearful ones are less often associated with diagnoses of agoraphobia, as well as many other Axis I disorders such as major depressive disorder, simple phobia and substance-related disorders.

LIMITATIONS

Recall bias and response bias may have distorted estimated relationships.

CONCLUSIONS

Although milder in terms of symptomatology and some comorbidity, clinicians need to pay appropriate attention to non-fearful subtypes of panic attacks which appear to be equally dysfunctional.

摘要

背景

无恐惧的惊恐发作是惊恐发作的一个亚组,不伴有主观恐惧体验。然而,以往研究大多在医疗环境下进行,且样本量较小。本研究旨在通过使用国家共病调查(NCS)数据库来澄清和扩展先前的研究结果,包括无恐惧惊恐发作的患病率和特征。

方法

从NCS的8098名原始受访者中,选取符合DSM-III-R终生惊恐发作诊断标准的受试者。其中,识别出无恐惧惊恐发作的个体,并与有恐惧惊恐发作的受试者进行比较。

结果

30%的惊恐发作发生时并无濒死或发疯的恐惧。尽管这些无恐惧的惊恐发作在年龄、发病年龄或发作频率方面与有恐惧的惊恐发作并无差异,但它们较少伴有一些症状,包括呼吸急促、颤抖、窒息感和人格解体,较少导致预期性焦虑,且较少接受药物治疗。尽管它们同样会导致惊恐障碍的诊断并造成同等程度的功能损害,但无恐惧的惊恐发作较少与广场恐惧症的诊断相关,也较少与许多其他轴I障碍相关,如重度抑郁症、单纯恐惧症和物质相关障碍。

局限性

回忆偏差和应答偏差可能扭曲了估计的关系。

结论

尽管在症状学和一些共病方面较为轻微,但临床医生需要适当关注无恐惧的惊恐发作亚型,它们似乎同样会导致功能障碍。

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