Kim Hyunggun, Chandran Krishnan B, Sacks Michael S, Lu Jia
Department of Biomedical Engineering, University of Iowa, Iowa City, IA 52242, USA.
Ann Biomed Eng. 2007 Jan;35(1):30-44. doi: 10.1007/s10439-006-9203-8. Epub 2006 Nov 2.
In order to achieve a more realistic and accurate computational simulation of native and bioprosthetic heart valve dynamics, a finite shell element model was developed. Experimentally derived and uncoupled in-plane and bending behaviors were implemented into a fully nonlinear stress resultant shell element. Validation studies compared the planar biaxial extension and three-point bending simulations to the experimental data and demonstrated excellent fidelity. Dynamic simulations of a pericardial bioprosthetic heart valve with the developed shell element model showed significant differences in the deformation characteristics compared to the simulation with an assumed isotropic bending model. The new finite shell element model developed in the present study can also incorporate various types of constitutive models and is expected to help us to understand the complex dynamics of native and bioprosthetic heart valve function in physiological and pathological conditions.
为了实现对天然心脏瓣膜和生物人工心脏瓣膜动力学更真实、准确的计算模拟，开发了一种有限壳单元模型。将实验得出的面内和面外弯曲行为解耦，并应用于一个完全非线性应力结果壳单元中。验证研究将平面双轴拉伸和三点弯曲模拟与实验数据进行了比较，结果显示具有出色的逼真度。使用所开发的壳单元模型对心包生物人工心脏瓣膜进行的动态模拟表明，与采用假定各向同性弯曲模型的模拟相比，其变形特征存在显著差异。本研究中开发的新有限壳单元模型还可以纳入各种类型的本构模型，有望帮助我们了解生理和病理条件下天然心脏瓣膜和生物人工心脏瓣膜功能的复杂动力学。
