Shafik A, Shafik A A
Department of Surgery and Experimental Research, Faculty of Medicine, Cairo University, Egypt.
Clin Exp Obstet Gynecol. 2006;33(3):174-7.
In a recent study we have demonstrated that semen deposition into the vagina or uterus effects uterine pressure rise which is suggested to assist in "sucking" semen into the uterine cavity. The purpose of this study was to investigate whether the uterine pressure rise is effected by the sperm or the substances contained in the seminal plasma, and to test the response of the vagina and uterus to abnormal semen deposition.
Semen was obtained from 60 men divided into four groups: A) obstructive azoospermia, B) Sertoli cell-only syndrome, C) oligozoospermia and D), fertile subjects. Before and after semen deposition into the vagina and uterus both vaginal and uterine pressure were recorded.
Semen from groups A and B produced no significant vaginal or uterine pressure changes (p > 0.05) when it was deposited into either the vagina or uterus. Group C and D semen when placed in the vagina or uterus separately effected significant intrauterine pressure rise (p < 0.05) but no vaginal pressure changes (p > 0.05). The pressure rise was higher when the semen was deposited in the uterus than in the vagina (p < 0.05) and with the normospermic than oligozoospermic semen (p < 0.05). In groups C and D, the seminal plasma produced no vaginal or uterine pressure changes (p > 0.05), whereas the sperm effected intrauterine pressure rise (p < 0.05) which was more elevated with sperm from normospermic than oligozoospermic semen (p < 0.05).
Aspermic semen did not effect vaginal or uterine pressure rise, while oligozoospermic and normospermic semen produced rise of uterine but not vaginal pressure. Uterine pressure rise was induced by the sperm and not the seminal plasma. Further studies are required to define the sulstances secreted by the sperm which produce this increased uterine pressure.
在最近的一项研究中，我们已经证明，将精液射入阴道或子宫会引起子宫压力升高，这被认为有助于将精液“吸入”子宫腔。本研究的目的是调查子宫压力升高是受精子还是精浆中所含物质的影响，并测试阴道和子宫对异常精液射入的反应。
从60名男性获取精液，分为四组：A）梗阻性无精子症，B）唯支持细胞综合征，C）少精子症，D）有生育能力的受试者。在将精液射入阴道和子宫前后，记录阴道和子宫压力。
A组和B组的精液射入阴道或子宫时，未引起阴道或子宫压力的显著变化（p>0.05）。C组和D组的精液分别置于阴道或子宫时，引起子宫内压力显著升高（p<0.05），但阴道压力无变化（p>0.05）。精液射入子宫时的压力升高高于射入阴道时（p<0.05），正常精子精液引起的压力升高高于少精子症精液（p<0.05）。在C组和D组中，精浆未引起阴道或子宫压力变化（p>0.05），而精子引起子宫内压力升高（p<0.05），正常精子精液的精子引起的压力升高比少精子症精液的精子更高（p<0.05）。
无精子精液不会引起阴道或子宫压力升高，而少精子症和正常精子精液会引起子宫压力升高，但不会引起阴道压力升高。子宫压力升高是由精子而非精浆引起的。需要进一步研究来确定精子分泌的导致子宫压力升高的物质。
