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骨骼强度的纳米颗粒起源

Nanogranular origins of the strength of bone.

作者信息

Tai Kuangshin, Ulm Franz-Josef, Ortiz Christine

机构信息

Department of Materials Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.

出版信息

Nano Lett. 2006 Nov;6(11):2520-5. doi: 10.1021/nl061877k.

DOI:10.1021/nl061877k
PMID:17090084
Abstract

Here, we investigate the ultrastructural origins of the strength of bone, which is critical for proper physiological function. A combination of dual nanoindentation, three-dimensional elastic-plastic finite element analysis using a Mohr-Coulomb cohesive-frictional strength criterion, and angle of repose measurements was employed. Our results suggest that nanogranular friction between mineral particles is responsible for increased yield resistance in compression relative to tension and that cohesion originates from within the organic matrix itself, rather than organic-mineral bonding.

摘要

在此,我们研究了对正常生理功能至关重要的骨强度的超微结构起源。我们采用了双纳米压痕、使用摩尔-库仑内聚-摩擦强度准则的三维弹塑性有限元分析以及休止角测量相结合的方法。我们的结果表明,矿物颗粒之间的纳米颗粒摩擦导致压缩时的屈服阻力相对于拉伸时增加,并且内聚力源自有机基质本身,而非有机-矿物键合。

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