Attin Rengin, Ilse Anika, Werner Carola, Wiegand Annette, Attin Thomas
Department of Operative Dentistry and Preventive Dentistry and Periodontology, University of Göttingen, Göttingen, Germany.
Angle Orthod. 2006 Nov;76(6):1022-7. doi: 10.2319/070605-218.
To evaluate the recolonization pattern of Mutans streptococci (ms) on densely colonized teeth with fixed orthodontic appliances after treatment with a highly concentrated (36%) chlorhexidine varnish.
Healthy subjects (n = 19) with fixed orthodontic appliances and high bacterial ms counts in saliva were recruited. In order to establish a baseline registration, plaque adjacent to brackets was sampled and cultivated on Dentocult strips. Following professional tooth cleaning, chlorhexidine varnish was applied on all teeth for 8 minutes. The degree of recolonization with ms was assessed 2 weeks after varnish application in plaque around the brackets. For statistical analysis, the data were subjected to a repeated measures design.
After 2 weeks, ms counts were reduced as compared to baseline values. However, the reduction only weakly met statistical significance (P = .049).
The application of a highly concentrated chlorhexidine varnish in patients with fixed orthodontic appliances does not result in a distinct reduction of ms numbers 2 weeks after treatment.
评估在使用高浓度（36%）氯己定清漆治疗后，变形链球菌（ms）在固定正畸矫治器密集定植牙齿上的再定植模式。
招募了佩戴固定正畸矫治器且唾液中ms细菌计数高的健康受试者（n = 19）。为建立基线记录，采集托槽附近的牙菌斑并在Dentocult试纸上培养。专业牙齿清洁后，在所有牙齿上涂抹氯己定清漆8分钟。在涂抹清漆2周后，评估托槽周围牙菌斑中ms的再定植程度。为进行统计分析，对数据采用重复测量设计。
2周后，ms计数与基线值相比有所降低。然而，这种降低仅微弱地达到统计学显著性（P = .049）。
在佩戴固定正畸矫治器的患者中应用高浓度氯己定清漆，治疗2周后ms数量并未显著减少。
