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高浓度洗必泰清漆治疗对佩戴固定正畸矫治器青少年的抗菌效果。

Antimicrobial effectiveness of a highly concentrated chlorhexidine varnish treatment in teenagers with fixed orthodontic appliances.

作者信息

Attin Rengin, Ilse Anika, Werner Carola, Wiegand Annette, Attin Thomas

机构信息

Department of Operative Dentistry and Preventive Dentistry and Periodontology, University of Göttingen, Göttingen, Germany.

出版信息

Angle Orthod. 2006 Nov;76(6):1022-7. doi: 10.2319/070605-218.

Abstract

OBJECTIVE

To evaluate the recolonization pattern of Mutans streptococci (ms) on densely colonized teeth with fixed orthodontic appliances after treatment with a highly concentrated (36%) chlorhexidine varnish.

MATERIALS AND METHODS

Healthy subjects (n = 19) with fixed orthodontic appliances and high bacterial ms counts in saliva were recruited. In order to establish a baseline registration, plaque adjacent to brackets was sampled and cultivated on Dentocult strips. Following professional tooth cleaning, chlorhexidine varnish was applied on all teeth for 8 minutes. The degree of recolonization with ms was assessed 2 weeks after varnish application in plaque around the brackets. For statistical analysis, the data were subjected to a repeated measures design.

RESULTS

After 2 weeks, ms counts were reduced as compared to baseline values. However, the reduction only weakly met statistical significance (P = .049).

CONCLUSIONS

The application of a highly concentrated chlorhexidine varnish in patients with fixed orthodontic appliances does not result in a distinct reduction of ms numbers 2 weeks after treatment.

摘要

目的

评估在使用高浓度(36%)氯己定清漆治疗后,变形链球菌(ms)在固定正畸矫治器密集定植牙齿上的再定植模式。

材料与方法

招募了佩戴固定正畸矫治器且唾液中ms细菌计数高的健康受试者(n = 19)。为建立基线记录,采集托槽附近的牙菌斑并在Dentocult试纸上培养。专业牙齿清洁后,在所有牙齿上涂抹氯己定清漆8分钟。在涂抹清漆2周后,评估托槽周围牙菌斑中ms的再定植程度。为进行统计分析,对数据采用重复测量设计。

结果

2周后,ms计数与基线值相比有所降低。然而,这种降低仅微弱地达到统计学显著性(P = .049)。

结论

在佩戴固定正畸矫治器的患者中应用高浓度氯己定清漆,治疗2周后ms数量并未显著减少。

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