Hou Huie Ming, Hägg Urban, Sam Kim, Rabie A B M, Wong Ricky W K, Lam B, Ip Mary S
Orthodontics, Faculty of Dentistry, The University of Hong Kong, Hong Kong, SAR, People's Republic of China.
Angle Orthod. 2006 Nov;76(6):962-9. doi: 10.2319/081005-273.
To evaluate dentofacial characteristics in relation to obesity and degree of severity of obstructive sleep apnea (OSA) in male Chinese patients and to elucidate the relationship between demographic parameters (age, body weight, height, and body mass index [BMI]) cephalometric parameters and OSA in these subjects.
Lateral cephalograms of 121 Chinese male patients in natural head posture were obtained. Based on BMI value, the patients were divided into three groups. Based on apnea-hypopnea index (AHI) value, the patients were divided into a mild-to-moderate and a severe group.
The hyoid position and soft palate length were significantly different among the three obesity groups. Soft palate length was significantly longer (P < .01) in the severe OSA group than in the mild-to-moderate OSA group. Tongue base was significantly more inferiorly placed (P < .05) in the severe OSA group than in the mild-to-moderate OSA group. Craniocervical extension was significantly increased (P < .05) in the severe OSA group. Statistically significant differences were found among the three obesity groups in mandibular length, mandibular body length, maxillary length, anterior cranial base length, and overbite. The multiple stepwise linear regression analysis identified body weight, lower posterior facial height, mandibular body length, craniocervical extension, and sella-hyoid distance as the significant predictive variables for AHI.
This study revealed the existence of craniofacial and upper airway soft tissue differences in relation to obesity and severity of OSA among male Chinese OSA patients. Body weight and certain cephalometric parameters were significant predictors of OSA in Chinese male subjects.
评估中国男性患者中牙颌面特征与肥胖及阻塞性睡眠呼吸暂停（OSA）严重程度之间的关系，并阐明这些受试者的人口统计学参数（年龄、体重、身高和体重指数[BMI]）、头影测量参数与OSA之间的关系。
获取121例自然头位的中国男性患者的侧位头影测量片。根据BMI值将患者分为三组。根据呼吸暂停低通气指数（AHI）值将患者分为轻至中度组和重度组。
三个肥胖组之间的舌骨位置和软腭长度存在显著差异。重度OSA组的软腭长度明显长于轻至中度OSA组（P <.01）。重度OSA组的舌根位置明显低于轻至中度OSA组（P <.05）。重度OSA组的颅颈伸展明显增加（P <.05）。三个肥胖组在下颌长度、下颌体长、上颌长度、前颅底长度和覆牙合方面存在统计学显著差异。多元逐步线性回归分析确定体重、下后面部高度、下颌体长、颅颈伸展和蝶鞍-舌骨距离为AHI的显著预测变量。
本研究揭示了中国男性OSA患者中与肥胖和OSA严重程度相关的颅面和上气道软组织差异。体重和某些头影测量参数是中国男性受试者OSA的重要预测指标。
