Tikku Tripti, Khanna Rohit, Sachan Kiran, Agarwal Akhil, Srivastava Kamna, Lal Anubha
Department of Orthodontics, Babu Banarasi Das College of Dental Sciences, Lucknow, Uttar Pradesh, India.
Dent Res J (Isfahan). 2016 Sep;13(5):396-404. doi: 10.4103/1735-3327.192273.
Obstructive Sleep Apnea (OSA) is a potentially life-threatening condition in which there is a periodic cessation of breathing (for 10 sec or longer) that occurs during sleep in the presence of inspiratory effort. The aim of the study was to assess volumetric and dimensional differences between OSA patients and normal individuals in the upright posture.
The present study was conducted on CBCT scans of 32 patients who were divided into two groups -Group I (control group) and Group II (OSA subjects). Group I consisted of 16 patients with normal airway with ESS score from 2 to 10, STOP BANG Questionnaire score of <3 and who had undergone CBCT for various diagnostic reasons. Group II had patients with ESS score >10, STOP BANG Questionnaire score of > 3, AHI index >5. Linear and angular parameters, volume and minimum cross-section area (MCA) of oropharyngeal airway, anteroposterior length and lateral width at MCA was compared amongst the groups.
The oropharyngeal volume, MCA, and the anteroposterior and lateral width of the airway at MCA of the OSA subjects was significantly lesser than that of normal subjects. The length of both soft palate and tongue was significantly more in Group II. The angle between the nasopharyngeal airway and the oropharyngeal airway was significantly more obtuse in Group II.
The reduction in oropharyngeal volume in OSA patients could be attributed to different anatomical and pathophysiological factors that were corroborated with the findings of the present study.
阻塞性睡眠呼吸暂停(OSA)是一种潜在的危及生命的疾病,其特征是在睡眠期间存在吸气努力时出现周期性呼吸停止(持续10秒或更长时间)。本研究的目的是评估OSA患者和正常个体在直立姿势下的容积和尺寸差异。
本研究对32例患者的CBCT扫描图像进行分析,这些患者被分为两组——第一组(对照组)和第二组(OSA受试者)。第一组由16例气道正常的患者组成,ESS评分在2至10之间,STOP BANG问卷评分<3,因各种诊断原因接受了CBCT检查。第二组患者的ESS评分>10,STOP BANG问卷评分>3,AHI指数>5。比较了两组之间的线性和角度参数、口咽气道的容积和最小横截面积(MCA)、MCA处的前后长度和侧向宽度。
OSA受试者的口咽容积、MCA以及MCA处气道的前后宽度和侧向宽度均显著小于正常受试者。第二组软腭和舌头的长度均显著更长。第二组中鼻咽气道与口咽气道之间的角度明显更钝。
OSA患者口咽容积的减小可能归因于不同的解剖学和病理生理学因素,本研究结果证实了这一点。