de Franchis Roberto
Am J Gastroenterol. 2006 Nov;101(11):2520-2. doi: 10.1111/j.1572-0241.2006.00880.x.
The possibility of identifying cirrhotic patients with esophageal varices by noninvasive means is attractive, because it would allow for the restriction of the performance of screening endoscopy to patients at high risk of having varices. Over the years, several studies addressing this issue have been performed with little success. The recently proposed platelet count/spleen diameter ratio appears to be the best noninvasive predictor of esophageal varices developed so far. However, the available evidence is not yet sufficient to allow for the modification of the current policy of screening cirrhotic patients by endoscopy at the time of diagnosis to detect varices.
通过非侵入性手段识别患有食管静脉曲张的肝硬化患者具有吸引力，因为这将使得筛查性内镜检查仅针对有静脉曲张高风险的患者进行。多年来，针对这一问题开展了多项研究，但成效甚微。最近提出的血小板计数/脾脏直径比值似乎是目前为止所发现的预测食管静脉曲张的最佳非侵入性指标。然而，现有证据仍不足以改变目前在肝硬化患者诊断时通过内镜检查筛查静脉曲张的现行策略。
