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脂褐素样荧光团源自丙二醛。

Lipofuscin-like fluorophores originated from malondialdehyde.

作者信息

Uchida Koji

机构信息

Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan.

出版信息

Free Radic Res. 2006 Dec;40(12):1335-8. doi: 10.1080/10715760600902302.

DOI:10.1080/10715760600902302
PMID:17090422
Abstract

The accumulation of fluorescent age pigment or lipofuscin is a frequently observed age-associated cellular alteration in a variety of post-mitotic cells of many species. These pigments are observed within granules composed, in part, of damaged protein and lipid. In the present mini-review, I provide a comprehensive summary of fluorescent adducts originated from malondialdehyde (MDA).

摘要

荧光衰老色素或脂褐素的积累是在许多物种的各种有丝分裂后细胞中经常观察到的与年龄相关的细胞改变。这些色素存在于部分由受损蛋白质和脂质组成的颗粒中。在本综述中，我全面总结了源自丙二醛（MDA）的荧光加合物。

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