[Serum alpha-1-fetoprotein in pregnancy in relation to length of gestation].

In a group of 310 immunoenzymatic examinations of MS AFP by the Sevatest ELISA AFP Micro I kit in 310 women with normal pregnancies the authors detected the exponential character of the rise of serum AFP up to the 35th week of pregnancy (or foetal length of 88 mm resp.): in relation to the foetal length according to equation y(mean) = 10.544 X 1.0369x (for x = 28 to 88 mm) and in relation to the gestation period according to formula y(mean) = 7.720 X 1.1097x (for x = 15 to 35 weeks). During the subsequent course of gestation a steady decline of levels occurs and in the 41st week the mean MS AFP values decline to the level of the 22nd week of gestation (in foetal length of 99 mm the levels correspond to that during foetal length of 55 mm).