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护士鲨（Ginglymostoma cirratum）肝脏中脂肪酸结合蛋白的分离与鉴定。

Isolation and characterization of fatty acid binding protein in the liver of the nurse shark, Ginglymostoma cirratum.

作者信息

Bass N M, Manning J A, Luer C A

机构信息

Department of Medicine, Liver Center, University of California, San Francisco 94143.

出版信息

Comp Biochem Physiol A Comp Physiol. 1991;98(2):355-62. doi: 10.1016/0300-9629(91)90547-p.

DOI:10.1016/0300-9629(91)90547-p
PMID:1709075
Abstract
  1. A 14.5 kDa fatty acid binding protein was isolated from the liver of the nurse shark, Ginglymostoma cirratum. 2. Purified shark liver FABP (pI = 5.4) bound oleic acid at a single site with an affinity similar to that of mammalian FABP. 3. The apparent size, pI and amino acid composition of shark liver FABP indicate a close structural relationship between this protein and mammalian heart FABP.
摘要
  1. 从护士鲨（长须鲨）的肝脏中分离出一种14.5 kDa的脂肪酸结合蛋白。2. 纯化后的鲨鱼肝脏脂肪酸结合蛋白（pI = 5.4）在单一结合位点结合油酸，其亲和力与哺乳动物脂肪酸结合蛋白相似。3. 鲨鱼肝脏脂肪酸结合蛋白的表观大小、pI和氨基酸组成表明该蛋白与哺乳动物心脏脂肪酸结合蛋白在结构上密切相关。

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