膀胱癌膀胱内卡介苗治疗后发生的肉芽肿性肝炎。

Granulomatous hepatitis after intravesical BCG treatment for bladder cancer.

作者信息

Ersoy Osman, Aran Rasit, Aydinli Musa, Yonem Ozlem, Harmanci Ozgur, Akdogan Bulent, Pinar Ahmet, Sokmensuer Cenk, Bayraktar Yusuf

机构信息

Department of Gastroenterology, Hacettepe University Faculty of Medicine, Ankara, Turkey.

出版信息

Indian J Gastroenterol. 2006 Sep-Oct;25(5):258-9.

PMID:17090848

Abstract

Intravesical bacillus Calmette-Guerin (BCG) is used in patients with urinary bladder carcinoma. Although it is generally well tolerated, granulomatous hepatitis is a rare but serious complication. We report a 42-year-old man and a 56-year-old man who developed granulomatous hepatitis following intravesical BCG. One of them was treated successfully with antitubercular therapy; the other died because of BCG sepsis and multi-organ failure.

摘要

膀胱内灌注卡介苗（BCG）用于膀胱癌患者。尽管其耐受性通常良好，但肉芽肿性肝炎是一种罕见却严重的并发症。我们报告了两名分别为42岁和56岁的男性，他们在膀胱内灌注BCG后发生了肉芽肿性肝炎。其中一人经抗结核治疗成功；另一人因BCG败血症和多器官衰竭死亡。