Macleod Liam C, Ngo Tin C, Gonzalgo Mark L
University of Washington School of Medicine, Seattle, WA;
Stanford University School of Medicine, Stanford, CA.
Can Urol Assoc J. 2014 Jul;8(7-8):E540-4. doi: 10.5489/cuaj.1411.
Intravesical Bacillus Calmette-Guérin (BCG) is an important treatment for the management of non-muscle invasive bladder cancer because of its proven efficacy and favourable safety profile. The most common complications associated with BCG treatment are relatively minor. They include urinary frequency, cystitis, fever, and hematuria. Although serious complications are rare, patients can develop severe, life-threatening sepsis with disseminated mycobacterial infection. We report a rare case of periurethral diverticulum formation after intravesical BCG and review the literature on the potential complications of this treatment modality.
膀胱内灌注卡介苗(BCG)是治疗非肌层浸润性膀胱癌的重要方法,因其疗效已得到证实且安全性良好。与卡介苗治疗相关的最常见并发症相对较轻,包括尿频、膀胱炎、发热和血尿。虽然严重并发症罕见,但患者可能会发生严重的、危及生命的播散性分枝杆菌感染败血症。我们报告1例膀胱内灌注卡介苗后发生尿道周围憩室形成的罕见病例,并复习有关这种治疗方式潜在并发症的文献。