Bansal Sanjay, Dhawan Anil
Paediatric Liver Centre King's College Hospital, Denmark Hill, London SE5 9RS, United Kingdom.
Indian J Pediatr. 2006 Oct;73(10):931-4. doi: 10.1007/BF02859289.
Acute liver failure in children is a rare but potentially fatal disease. Causes of ALF in neonatal period are different from those in early or late childhood. Despite the improvement in the paediatric intensive care, liver transplantation remains the only effective treatment. Use of newer treatment modalities (liver assist devices and hepatocyte transplantation) is still in experimental phase. Management requires early recognition, prompt diagnosis of treatable condition, supportive therapy and prevention of complications hence these children should ideally be treated in a specialist unit.
儿童急性肝衰竭是一种罕见但可能致命的疾病。新生儿期急性肝衰竭的病因与儿童早期或晚期不同。尽管儿科重症监护有所改善，但肝移植仍然是唯一有效的治疗方法。使用更新的治疗方式（肝辅助装置和肝细胞移植）仍处于实验阶段。管理需要早期识别、及时诊断可治疗的情况、支持性治疗和预防并发症，因此这些儿童理想情况下应在专科单位接受治疗。
