Ardavanis Alexandros, Orphanos George, Ioannidis George, Rigatos Gerassimos
First Department of Medical Oncology, St. Savvas Anticancer Hospital, Athens, Greece.
In Vivo. 2006 Sep-Oct;20(5):671-3.
Skin metastasis from lung cancer is an unusual event carrying an ominous prognosis. Three cases with non-small cell lung cancer (NSCLC) with skin involvement and rapidly fatal clinical course due to extensive CNS metastasis are reported. The eventual association of skin metastases and a phenotype with "CNS-predilection" or an aggressive phase of NSCLC are discussed.
肺癌皮肤转移是一种罕见事件,预后不佳。本文报告了3例非小细胞肺癌(NSCLC)伴有皮肤受累且因广泛中枢神经系统转移而临床病程迅速致死的病例。文中讨论了皮肤转移与具有“中枢神经系统倾向”的表型或NSCLC侵袭期之间的最终关联。