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[大鼠视皮层中γ-氨基丁酸能的还原型辅酶Ⅱ黄递酶阳性的马丁诺蒂细胞]

[Gabaergic NADPH-diaphorase-positive Martinotti cells in the visual cortex in rats].

作者信息

Hedlich A, Lüth H J, Werner L, Bär B, Hanisch U, Winkelmann E

机构信息

Paul-Flechsig-Institut für Hirnforschung, Abteilung Neuroanatomie, Karl-Marx-Universität Leipzig.

出版信息

J Hirnforsch. 1990;31(6):681-7.

PMID:1709186
Abstract

NADPH-diaphorase positive cells were described in the visual cortex of the rat in layers II-VI and in the white matter. Their somata were large or medium-sized, oval or elongated, and their cytoplasm was accumulated at the poles. Some proximal thickened coarse dendrites formed a bitufted dendritic field. These features showed a cell type impregnated with the Golgi-Kopsch-method and a Golgi-deimpregnation-method described as Martinotti cell (sparsely spined polarized neurons with ascending axons). The immunocytochemical evidence of GABA in NADPH-diaphorase positive neurons (double labeling) showed the GABA ergic nature of these cells, but an attempt for a double labelling of NADPH-diaphorase and Parvalbumin was negative.

摘要

在大鼠视觉皮层的II-VI层及白质中发现了NADPH黄递酶阳性细胞。它们的胞体大或中等大小,呈椭圆形或细长形,细胞质聚集在两极。一些近端增厚的粗树突形成了双丛状树突野。这些特征显示出一种用高尔基-科普施方法和高尔基脱染法标记的细胞类型,被描述为马丁诺蒂细胞(具有上升轴突的稀疏棘状极化神经元)。NADPH黄递酶阳性神经元中GABA的免疫细胞化学证据(双重标记)显示了这些细胞的GABA能性质,但NADPH黄递酶和小白蛋白的双重标记尝试为阴性。

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