Erbagci Zülal, Tuncel Almla, Bayram Nazan, Erkilic Suna, Bayram Aysen
Departments of Dermatology, Gaziantep University Medical Faculty, Gaziantep, Turkey.
J Dermatolog Treat. 2006;17(5):314-8. doi: 10.1080/09546630600900043.
Tuberculosis verrucosa cutis (TBVC) is a rare form of skin tuberculosis in Western communities, and is generally seen in certain risk groups. A 52-year-old housewife with recalcitrant generalized cutaneous and mucosal lichen planus (LP) of more than a 20-year duration presented with an erythematous-edematous plaque with a warty surface containing deep hemorrhagic fissures and numerous orifices draining purulent material on the back of her left hand. On the basis of clinical, histological and bacteriological findings, TBVC was diagnosed. The patient was successfully treated with isoniazid, rifampicin, ethambutol and pyrazinamide. Interestingly, all lichen lesions improved completely with this therapy. To the best of our knowledge, this is the first documented case of TBVC associated with LP, which was cured by antitubercular polychemotherapy. The case is presented because it reflects a possible reciprocal causal relationship between two cutaneous conditions of different natures.
疣状皮肤结核(TBVC)在西方社会是一种罕见的皮肤结核形式,通常见于某些高危人群。一名52岁的家庭主妇,患有顽固的泛发性皮肤和黏膜扁平苔藓(LP)超过20年,其左手背部出现一个红斑水肿性斑块,表面呈疣状,有深部出血性裂隙以及多个排出脓性物质的小孔。根据临床、组织学和细菌学检查结果,诊断为疣状皮肤结核。该患者接受异烟肼、利福平、乙胺丁醇和吡嗪酰胺治疗后痊愈。有趣的是,所有扁平苔藓皮损在该治疗后完全改善。据我们所知,这是首例有文献记载的与扁平苔藓相关的疣状皮肤结核病例,通过抗结核联合化疗得以治愈。呈现该病例是因为它反映了两种不同性质的皮肤疾病之间可能存在的相互因果关系。