Montes-De-Oca-Sánchez Griselda, Tirado-Sánchez Andrés, García-Ramírez Vicente
Service of Dermatology, Hospital General de México, DF, México.
J Dermatolog Treat. 2006;17(5):319-20. doi: 10.1080/09546630600944116.
Porokeratosis of Mibelli is a rare genodermatosis characterized by a disorder of keratinization. None of the currently available therapies is effective in all cases and this situation exposes the patient to multiple treatment cycles. We describe the successful use of topical imiquimod 5% cream in the management of porokeratosis of Mibelli of the axillae in a 12-year-old girl. Treatment with imiquimod was effective, probably due to the area of application, where large hydrated skin folds are found, which helps penetration of the drug on the stratum corneum.
米贝利汗孔角化症是一种罕见的遗传性皮肤病，其特征为角化异常。目前可用的治疗方法均不能在所有病例中有效，这种情况使患者面临多个治疗周期。我们描述了一名12岁女孩腋窝部米贝利汗孔角化症患者成功使用5%咪喹莫特乳膏治疗的情况。咪喹莫特治疗有效，可能是由于应用部位，该部位存在大量湿润的皮肤褶皱，有助于药物渗透到角质层。
