Ruland W O, Schwering L, Steffen W, Mühlschlegel A
Chirurgische Abteilung, Städt, Krankenhauses Marienhospital, Arnsberg.
Aktuelle Traumatol. 1991 Feb;21(1):24-7.
An open randomized study design was used to compare the soft-tissue swelling in patients with fibular capsule injuries under therapy with Chomelanum (preparation A), Lasonil (preparation B) and ointment base of Chomelanum (preparation C). 90 patients were selected for participation in the study, and the results of 85 patients were available for evaluation. Concerning the initial condition there was no significant difference between the three therapy groups of the study. Assessment criteria were the difference of circumference in plane of ankle joint (injured/uninjured side) and the difference of soft-tissue above lateral malleoulus in sonography. The study showed that preparation A had a significantly larger influence on soft tissue detumescence than preparation B- and B larger than C. In observation period all patients of group B and C still showed soft tissue swelling. Between third and fourth day of treatment half of patients in group A did not need any treatment because of complete detumescence. In all assessment criteria significant differences in favor of preparation A were observed.
采用开放随机研究设计,比较使用Chomelanum(制剂A)、Lasonil(制剂B)和Chomelanum软膏基质(制剂C)治疗的腓骨囊损伤患者的软组织肿胀情况。选取90例患者参与研究,85例患者的结果可供评估。关于初始状况,研究的三个治疗组之间无显著差异。评估标准为踝关节平面(患侧/健侧)周长差异以及超声检查中外踝上方软组织差异。研究表明,制剂A对软组织消肿的影响明显大于制剂B,制剂B大于制剂C。在观察期内,B组和C组的所有患者仍表现出软组织肿胀。治疗的第三天至第四天,A组一半的患者因肿胀完全消退而无需任何治疗。在所有评估标准中,均观察到有利于制剂A的显著差异。