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事件本体:一种以通路为中心的生物过程本体。

Event ontology: a pathway-centric ontology for biological processes.

作者信息

Kushida Tatsuya, Takagi Toshihisa, Fukuda Ken Ichiro

机构信息

Institute for Bioinformatics Research and Development, Japan Science and Technology Agency, AIST Bio-IT Research Building, 2-42 Aomi, Koutou-ku, Tokyo 135-0064, Japan.

出版信息

Pac Symp Biocomput. 2006:152-63.

Abstract

Event ontology is a new biomedical ontology developed to annotate pathway components in a pathway database. It organizes the concepts and terms of sub-pathways, pathways, biological phenomena, experimental conditions, medications, and external stimuli appearing in biological pathways (e.g. signal transduction, disease-, metabolic-, molecular interaction-, genetic interaction pathways, etc.). Concepts in the Event ontology are extracted manually from scientific literature. Each term has links to external databases such as Gene Ontology, Reactome, KEGG, BioCyc, and PubMed.

摘要

事件本体是一种新开发的生物医学本体,用于注释通路数据库中的通路组件。它组织生物通路(如信号转导、疾病、代谢、分子相互作用、基因相互作用通路等)中出现的子通路、通路、生物现象、实验条件、药物和外部刺激的概念和术语。事件本体中的概念是从科学文献中手动提取的。每个术语都链接到外部数据库,如基因本体、Reactome、KEGG、BioCyc和PubMed。

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