Mandel Susan J, Mandel Louis
Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania Medical School, Philadelphia, PA, USA.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Feb;103(2):e43-7. doi: 10.1016/j.tripleo.2006.08.004. Epub 2006 Nov 7.
Radioactive iodine (131I), used in the treatment of differentiated thyroid carcinoma, is known to cause both short-term and long-term radiation damage to the salivary glands. The injury appears as glandular swellings and/or decreased salivation with 131I dosage and passage of time playing significant roles. A case report is presented to alert the profession to the existence of patients who have received 131I therapy and who complain shortly thereafter of xerostomia, but following a thorough examination are found to represent a group of false-positives. Emphasis is placed on the diagnostic techniques used in the differential diagnosis.
放射性碘（131I）用于治疗分化型甲状腺癌，已知会对唾液腺造成短期和长期辐射损伤。随着131I剂量的增加和时间的推移，损伤表现为腺体肿胀和/或唾液分泌减少，这两个因素起着重要作用。本文报告一例病例，以提醒业内人士注意，有患者接受131I治疗后不久抱怨口干，但经过全面检查发现这是一组假阳性病例。重点介绍了鉴别诊断中使用的诊断技术。
