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分子吸附循环系统在登革出血热所致急性肝衰竭中的应用

Use of molecular adsorbent recirculating system in acute liver failure attributable to dengue hemorrhagic fever.

作者信息

Penafiel Alvin, Devanand Anantham, Tan Han Khim, Eng Philip

机构信息

Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore.

出版信息

J Intensive Care Med. 2006 Nov-Dec;21(6):369-71. doi: 10.1177/0885066606293384.

Abstract

Fulminant liver failure is an uncommon but life-threatening complication of severe dengue infection. Molecular adsorbent recirculating system (MARS), which reverses hepatic encephalopathy, is an emerging important element in the armamentarium of organ support in the intensive care unit in patients suffering from acute liver failure. We report an intensive care unit case of fulminant liver failure secondary to dengue hemorrhagic fever, which was supported with MARS. MARS led to rapid reversal of biochemical profile and encephalopathy, resulting in early extubation and intensive care unit discharge.

摘要

暴发性肝衰竭是严重登革热感染的一种罕见但危及生命的并发症。分子吸附循环系统(MARS)可逆转肝性脑病,是重症监护病房中急性肝衰竭患者器官支持手段中的一个重要新要素。我们报告了1例登革出血热继发暴发性肝衰竭的重症监护病房病例,该病例接受了MARS支持治疗。MARS使生化指标和脑病迅速逆转,实现了早期拔管和重症监护病房转出。

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