Mrázek Jan, Xie Shaohua
Department of Microbiology and Institute of Bioinformatics, University of Georgia, Athens, GA 30602, USA.
Bioinformatics. 2006 Dec 15;22(24):3099-100. doi: 10.1093/bioinformatics/btl551. Epub 2006 Nov 8.
We present a new tool for finding local sequence patterns in long DNA sequences. The program, Pattern Locator, uses an intuitive syntax for pattern description, and provides more flexibility than existing programs by allowing combinations of specific nucleotide sequences, direct and inverted repeats, variable length tandem repeats of subpatterns, and a specified number of errors in any part of the pattern.
The program is available for download and as a web service accessible through a CGI interface at http://www.cmbl.uga.edu/software.html. The source code is written in C and distributed under the GNU General Public License.
我们提出了一种用于在长DNA序列中寻找局部序列模式的新工具。该程序“模式定位器”使用直观的语法来描述模式,并且通过允许特定核苷酸序列、正向和反向重复、子模式的可变长度串联重复以及模式任何部分的指定数量错误的组合,比现有程序提供了更大的灵活性。
该程序可通过http://www.cmbl.uga.edu/software.html的CGI接口下载并作为网络服务使用。源代码用C编写,并根据GNU通用公共许可证分发。