Georgopoulos Gerasimos T, Halkiadakis Ioannis, Patsea Eleni, Papakonstantinou Dimitrios, Alexiou Michalis, Vergados Ioannis, Andreanos Dimitrios, Theodossiadis George, Moschos Michalis
Department of Ophthalmology, Medical School, University of Athens, Athens, Greece.
Ophthalmologica. 2006;220(6):361-7. doi: 10.1159/000095861.
To compare and correlate retinal nerve fiber layer (RNFL) measurements obtained by scanning laser polarimetry (SLP) with defects detected by short-wavelength automatic perimetry (SWAP) in eyes with ocular hypertension (OHT).
SLP and SWAP were performed in 96 eyes of 48 consecutive patients with OHT.
Twenty-five eyes (26%) had SWAP visual field defects. Twenty-seven eyes (28.1%) had abnormal RNFL evaluation defined by the GDx neural network ('number' > 29). Fourteen eyes of 10 patients (14.5%) had abnormal RNFL evaluation and SWAP visual field defects. RNFL thickness measurements were significantly reduced in eyes with abnormal SWAP. A weak but statistically significant correlation between the 'number' and pattern standard deviation (r = 0.3, p = 0.006) and the corrected pattern standard deviation (r = 0.3, p = 0.007) in SWAP was found. Areas of abnormal RNFL thickness corresponded to the localization of the SWAP visual field defects in corrected pattern deviation plots in 10 of the 14 eyes with defects in both tests.
SWAP visual field defects frequently coexist and correspond with abnormalities of RNFL detected by SLP in eyes with OHT. In certain eyes, however, the two methods detect different glaucoma properties.
比较并关联扫描激光偏振仪（SLP）测得的视网膜神经纤维层（RNFL）厚度与短波长自动视野计（SWAP）在高眼压症（OHT）患者眼中检测到的缺损情况。
对48例连续的OHT患者的96只眼睛进行了SLP和SWAP检查。
25只眼睛（26%）存在SWAP视野缺损。27只眼睛（28.1%）的RNFL评估异常，由GDx神经网络定义（“数值”>29）。10例患者的14只眼睛（14.5%）存在RNFL评估异常和SWAP视野缺损。SWAP异常的眼睛中RNFL厚度测量值显著降低。在SWAP中，发现“数值”与模式标准差（r = 0.3，p = 0.006）以及校正模式标准差（r = 0.3，p = 0.007）之间存在微弱但具有统计学意义的相关性。在两项检查均有缺损的14只眼睛中的10只眼睛中，RNFL厚度异常区域与校正模式偏差图中SWAP视野缺损的定位相对应。
在OHT患者眼中，SWAP视野缺损经常共存且与SLP检测到的RNFL异常相对应。然而，在某些眼睛中，这两种方法检测到不同的青光眼特征。
