丙型肝炎感染的注射吸毒患者的治疗挑战。
Therapeutic challenges in hepatitis C-infected injection drug using patients.
作者信息
Cooper Curtis L, Mills Edward J
机构信息
Ottawa Hospital, Division of Infectious Diseases, Canada.
出版信息
Harm Reduct J. 2006 Nov 10;3:31. doi: 10.1186/1477-7517-3-31.
Abstract
Hepatitis C Viral (HCV) infection in the injection drug user (IDU) population is a major medical concern. Concurrent substance abuse, co-morbid mental health conditions, poor socioeconomic status and a complex treatment protocol that is often incompatible with the life styles of IDUs combine to account for poor uptake and completion of HCV treatment. This article discusses HCV antiviral treatment issues relevant to IDUs chronically infected with this virus. The effect of non-injected substances of abuse on treatment outcome is considered. Priority issues requiring research are discussed.
摘要
注射吸毒人群中的丙型肝炎病毒（HCV）感染是一个主要的医学问题。同时存在的药物滥用、共病的心理健康状况、社会经济地位低下以及复杂的治疗方案（该方案往往与注射吸毒者的生活方式不相容）共同导致了HCV治疗的接受率低和完成率低。本文讨论了与长期感染该病毒的注射吸毒者相关的HCV抗病毒治疗问题。文中考虑了非注射滥用药物对治疗结果的影响。还讨论了需要开展研究的重点问题。
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