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中央脊髓损伤:病理生理学、治疗及预后

Central cord injury: pathophysiology, management, and outcomes.

作者信息

Harrop James S, Sharan Ashwini, Ratliff Jonathon

机构信息

Department of Neurosurgery, Jefferson Medical College, 909 Walnut St., 2nd Floor, Philadelphia, PA 19107, USA.

出版信息

Spine J. 2006 Nov-Dec;6(6 Suppl):198S-206S. doi: 10.1016/j.spinee.2006.04.006.

Abstract

BACKGROUND CONTEXT

Cervical spinal trauma can result in a heterogeneous collection of spinal cord injury syndromes. Acute traumatic central cord syndrome is a common category of which no uniform consensus on the etiology, pathophysiology, and treatment exists.

PURPOSE

To evaluate and review potential pathophysiology, current treatment options, and management of central cord injuries.

STUDY DESIGN

Comprehensive literature review and clinical experience.

METHODS

A systematic review of Medline for articles related to central cord and spinal cord injury was conducted up to and including journal articles published in September 2005.

CONCLUSIONS

Central cord injuries is a clinical definition which is composed of a heterogeneous population for which medical management and surgical decompression and stabilization provide improved neurologic recovery.

摘要

背景

颈椎脊髓损伤可导致多种脊髓损伤综合征。急性创伤性中央脊髓综合征是其中常见的一类,目前在病因、病理生理学及治疗方面尚无统一的共识。

目的

评估并综述中央脊髓损伤潜在的病理生理学、当前的治疗选择及处理方法。

研究设计

综合文献综述及临床经验。

方法

对Medline进行系统检索,纳入截至2005年9月发表的与中央脊髓和脊髓损伤相关的期刊文章。

结论

中央脊髓损伤是一个临床定义,涵盖了多种不同情况的患者群体,内科治疗以及手术减压和固定可改善其神经功能恢复。

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